Literature DB >> 22690664

Epigenetic mechanisms in gastric cancer.

Carolina Oliveira Gigek1, Elizabeth Suchi Chen, Danielle Queiroz Calcagno, Fernanda Wisnieski, Rommel Rodriguez Burbano, Marilia Arruda Cardoso Smith.   

Abstract

Cancer is considered one of the major health issues worldwide, and gastric cancer accounted for 8% of total cases and 10% of total deaths in 2008. Gastric cancer is considered an age-related disease, and the total number of newly diagnosed cases has been increasing as a result of the higher life expectancy. Therefore, the basic mechanisms underlying gastric tumorigenesis is worth investigation. This review provides an overview of the epigenetic mechanisms, such as DNA methylation, histone modifications, chromatin remodeling complex and miRNA, involved in gastric cancer. As the studies in gastric cancer continue, the mapping of an epigenome code is not far for this disease. In conclusion, an epigenetic therapy might appear in the not too distant future.

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Year:  2012        PMID： 22690664     DOI： 10.2217/epi.12.22

Source DB:  PubMed          Journal:  Epigenomics        ISSN： 1750-192X            Impact factor:   4.778


  44 in total

1.  Epidermal growth factor receptor-coamplified and overexpressed protein (VOPP1) is a putative oncogene in gastric cancer.

Authors:  Caiping Gao; Minghui Pang; Zhou Zhou; Size Long; Dandan Dong; Jiyun Yang; Mei Cao; Chumin Zhang; Shengxi Han; Liangping Li
Journal:  Clin Exp Med       Date:  2014-11-15       Impact factor: 3.984

2.  Association of COX2 gene hypomethylation with intestinal type gastric cancer in samples of patients from northern Brazil.

Authors:  Cynthia Farias Vieira de Melo; Carolina Oliveira Gigek; Juarez Nóbrega da Silva; Marilia de Arruda Cardoso Smith; Rubistenia Miranda de Araújo; Rommel Rodríguez Burbano; Eleonidas Moura Lima
Journal:  Tumour Biol       Date:  2013-09-07

Review 3.  MicroRNAs in gastric cancer: from benchtop to bedside.

Authors:  Fuyi Tong; Peng Cao; Yuan Yin; Suhua Xia; Rensheng Lai; Shenlin Liu
Journal:  Dig Dis Sci       Date:  2013-10-10       Impact factor: 3.199

Review 4.  DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer.

Authors:  Yuji Toiyama; Yoshinaga Okugawa; Ajay Goel
Journal:  Biochem Biophys Res Commun       Date:  2014-08-13       Impact factor: 3.575

5.  Reduced mRNA expression levels of MBD2 and MBD3 in gastric carcinogenesis.

Authors:  Thaís Brilhante Pontes; Elizabeth Suchi Chen; Carolina Oliveira Gigek; Danielle Queiroz Calcagno; Fernanda Wisnieski; Mariana Ferreira Leal; Samia Demachki; Paulo Pimentel Assumpção; Ricardo Artigiani; Laércio Gomes Lourenço; Rommel Rodriguez Burbano; Marília Arruda Cardoso Smith
Journal:  Tumour Biol       Date:  2013-12-13

6.  MiR-330-3p inhibits gastric cancer progression through targeting MSI1.

Authors:  Aoran Guan; Hui Wang; Xun Li; Hui Xie; Ruotian Wang; Yankun Zhu; Ruhong Li
Journal:  Am J Transl Res       Date:  2016-11-15       Impact factor: 4.060

Review 7.  Epigenetic modifications induced by Helicobacter pylori infection through a direct microbe-gastric epithelial cells cross-talk.

Authors:  Lorenzo Chiariotti; Tiziana Angrisano; Simona Keller; Ermanno Florio; Ornella Affinito; Pierlorenzo Pallante; Cinzia Perrino; Raffaela Pero; Francesca Lembo
Journal:  Med Microbiol Immunol       Date:  2013-05-29       Impact factor: 3.402

Review 8.  DNA and histone methylation in gastric carcinogenesis.

Authors:  Danielle Queiroz Calcagno; Carolina Oliveira Gigek; Elizabeth Suchi Chen; Rommel Rodriguez Burbano; Marília de Arruda Cardoso Smith
Journal:  World J Gastroenterol       Date:  2013-02-28       Impact factor: 5.742

Review 9.  What gastric cancer proteomic studies show about gastric carcinogenesis?

Authors:  Mariana Ferreira Leal; Fernanda Wisnieski; Carolina de Oliveira Gigek; Leonardo Caires do Santos; Danielle Queiroz Calcagno; Rommel Rodriguez Burbano; Marilia Cardoso Smith
Journal:  Tumour Biol       Date:  2016-04-28

Review 10.  An updated review of gastric cancer in the next-generation sequencing era: insights from bench to bedside and vice versa.

Authors:  Hiroyuki Yamamoto; Yoshiyuki Watanabe; Tadateru Maehata; Ryo Morita; Yoshihito Yoshida; Ritsuko Oikawa; Shinya Ishigooka; Shun-Ichiro Ozawa; Yasumasa Matsuo; Kosuke Hosoya; Masaki Yamashita; Hiroaki Taniguchi; Katsuhiko Nosho; Hiromu Suzuki; Hiroshi Yasuda; Yasuhisa Shinomura; Fumio Itoh
Journal:  World J Gastroenterol       Date:  2014-04-14       Impact factor: 5.742
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