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Literature DB >> 22689788

Cardiac actions of protein kinase C isoforms.

Abstract

Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury. This review focuses on newer concepts regarding PKC isoform-specific activation mechanisms and actions that have implications for the development of PKC-targeted therapeutics.

Entities: Chemical Disease Gene Mutation Species

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Year: 2012 PMID： 22689788 PMCID： PMC3582339 DOI： 10.1152/physiol.00009.2012

Source DB: PubMed Journal: Physiology (Bethesda) ISSN： 1548-9221

82 in total

1. Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity.

Authors: Akira Mima; Yuzuru Ohshiro; Munehiro Kitada; Motonobu Matsumoto; Pedro Geraldes; Chenzhong Li; Qian Li; Gregory S White; Christopher Cahill; Christian Rask-Madsen; George L King
Journal: Kidney Int Date: 2011-01-12 Impact factor: 10.612

2. Receptor-independent cardiac protein kinase Calpha activation by calpain-mediated truncation of regulatory domains.

Authors: Min-Young Kang; Yan Zhang; Scot J Matkovich; Abhinav Diwan; Athar H Chishti; Gerald W Dorn
Journal: Circ Res Date: 2010-08-05 Impact factor: 17.367

3. Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes.

Authors: Jianfen Guo; Lin Cong; Vitalyi O Rybin; Zoya Gertsberg; Susan F Steinberg
Journal: Am J Physiol Cell Physiol Date: 2010-08-04 Impact factor: 4.249

4. Receptor-independent protein kinase C alpha (PKCalpha) signaling by calpain-generated free catalytic domains induces HDAC5 nuclear export and regulates cardiac transcription.

Authors: Yan Zhang; Scot J Matkovich; Xiujun Duan; Abhinav Diwan; Min-Young Kang; Gerald W Dorn
Journal: J Biol Chem Date: 2011-06-03 Impact factor: 5.157

5. Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.

Authors: Hercules Apostolatos; André Apostolatos; Timothy Vickers; James E Watson; Shijie Song; Fernando Vale; Denise R Cooper; Juan Sanchez-Ramos; Niketa A Patel
Journal: J Biol Chem Date: 2010-06-14 Impact factor: 5.157

6. Interaction with AKAP79 modifies the cellular pharmacology of PKC.

Authors: Naoto Hoshi; Lorene K Langeberg; Christine M Gould; Alexandra C Newton; John D Scott
Journal: Mol Cell Date: 2010-02-26 Impact factor: 17.970

7. Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes.

Authors: Jianfen Guo; Zoya Gertsberg; Nazira Ozgen; Abdelkarim Sabri; Susan F Steinberg
Journal: J Biol Chem Date: 2010-12-14 Impact factor: 5.157

8. G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.

Authors: Ricky Malhotra; Karen M D'Souza; Michelle L Staron; Konstantin G Birukov; Ilona Bodi; Shahab A Akhter
Journal: J Biol Chem Date: 2010-03-01 Impact factor: 5.157

9. PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.

Authors: Carlos Hidalgo; Bryan Hudson; Julius Bogomolovas; Yi Zhu; Brian Anderson; Marion Greaser; Siegfried Labeit; Henk Granzier
Journal: Circ Res Date: 2009-08-13 Impact factor: 17.367

10. Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.

Authors: Viola Kooij; Nicky Boontje; Ruud Zaremba; Kornelia Jaquet; Cris dos Remedios; Ger J M Stienen; Jolanda van der Velden
Journal: Basic Res Cardiol Date: 2009-08-05 Impact factor: 17.165

44 in total

Review 1. KATP Channels in the Cardiovascular System.

Authors: Monique N Foster; William A Coetzee
Journal: Physiol Rev Date: 2016-01 Impact factor: 37.312

Review 2. Protein kinase C mechanisms that contribute to cardiac remodelling.

Authors: Alexandra C Newton; Corina E Antal; Susan F Steinberg
Journal: Clin Sci (Lond) Date: 2016-09-01 Impact factor: 6.124

3. A H(a)rd Way to Adapt in Cardiac Hypertrophy.

Authors: Haipeng Sun; Chen Gao; Yibin Wang
Journal: Circ Res Date: 2015-08-28 Impact factor: 17.367

4. The central role of protein kinase C epsilon in cyanide cardiotoxicity and its treatment.

Authors: Joseph Y Cheung; Salim Merali; JuFang Wang; Xue-Qian Zhang; Jianliang Song; Carmen Merali; Dhanendra Tomar; Hanning You; Annick Judenherc-Haouzi; Philippe Haouzi
Journal: Toxicol Sci Date: 2019-06-07 Impact factor: 4.849

5. Trophoblast cell surface antigen 2 (Trop-2) phosphorylation by protein kinase C α/δ (PKCα/δ) enhances cell motility.

Authors: Yugo Mori; Kaoru Akita; Kazuki Ojima; Shungo Iwamoto; Tomoko Yamashita; Eiichi Morii; Hiroshi Nakada
Journal: J Biol Chem Date: 2019-06-07 Impact factor: 5.157

6. K(ATP) channel gain-of-function leads to increased myocardial L-type Ca(2+) current and contractility in Cantu syndrome.

Authors: Mark D Levin; Gautam K Singh; Hai Xia Zhang; Keita Uchida; Beth A Kozel; Phyllis K Stein; Atilla Kovacs; Ruth E Westenbroek; William A Catterall; Dorothy Katherine Grange; Colin G Nichols
Journal: Proc Natl Acad Sci U S A Date: 2016-05-31 Impact factor: 11.205