| Literature DB >> 2268973 |
H Yanagi1, Y Shimakura, Y Yamanouchi, Y Watanabe, S Tsuchiya, H Hamaguchi.
Abstract
To investigate the association of apolipoprotein (APO) E4 and hypercholesterolemia in children, we studied the APOE phenotypes of 51 school-age children with hypercholesterolemia and of 51 age, sex and obesity index-matched controls with normocholesterolemia by two-dimensional gel electrophoresis APOE4 was present in 21 of 51 hypercholesterolemic children (41.2%), and in nine of 51 control subjects (17.6%). The difference was significant (p less than 0.01). This finding indicates that APOE4 is associated with hypercholesterolemia in children.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2268973 DOI： 10.1111/j.1399-0004.1990.tb03579.x
Source DB: PubMed Journal: Clin Genet ISSN： 0009-9163 Impact factor: 4.438