Literature DB >> 22689275

An unusual cause of hearing loss in an 81-year-old man.

Elizabeth Waldegrave1, Felicity Avann, Kuljeet Bhamra, Richard Stevens.   

Abstract

An 81-year-old man presented to accident and emergency with a recent history of rapidly progressive bilateral hearing loss. Further questioning revealed recent sinusitis, fevers and general malaise. Initial bloods showed raised inflammatory markers, raised creatinine, low albumin and urine dip was positive for blood and protein. Chest x-ray showed faint bilateral mid-zone infiltrates. He was treated with intravenous methylprednisolone (500 mg×3) for presumed Wegener's granulomatosis which was later confirmed by c-anti-neutrophil cytoplasmic antibodies testing (proteinase-3 positive) and supportive findings on CT chest and sinuses. He was discharged after 10 days in hospital on oral prednisolone and cyclophosphamide. He is continuing treatment and seen regularly in outpatient follow-up. Unfortunately his hearing has not fully recovered and he is awaiting a hearing aid.

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Year:  2011        PMID: 22689275      PMCID: PMC3166583          DOI: 10.1136/bcr.05.2011.4212

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  Otologic manifestations of Wegener's granulomatosis.

Authors:  Dai Takagi; Yuji Nakamaru; Shiroh Maguchi; Yasushi Furuta; Satoshi Fukuda
Journal:  Laryngoscope       Date:  2002-09       Impact factor: 3.325

2.  BSR and BHPR guidelines for the management of adults with ANCA associated vasculitis.

Authors:  C Lapraik; R Watts; P Bacon; D Carruthers; K Chakravarty; D D'Cruz; L Guillevin; L Harper; D Jayne; R Luqmani; J Mooney; D Scott
Journal:  Rheumatology (Oxford)       Date:  2007-09-05       Impact factor: 7.580

3.  The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources.

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Journal:  Arthritis Rheum       Date:  1996-01

Review 4.  Pathogenesis of ANCA-associated vasculitides.

Authors:  Cees G M Kallenberg
Journal:  Ann Rheum Dis       Date:  2011-03       Impact factor: 19.103

5.  Unusual Presentations of Wegener's granulomatosis: Pitfalls in Early Diagnosis.

Authors:  Syed Mansoor Ahmed Shah; Malik Anas Rabbani; Ambreen Gul; Aasim Ahmad
Journal:  Saudi J Kidney Dis Transpl       Date:  2003 Apr-Jun

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Authors:  T V McCaffrey; T J McDonald; G W Facer; R A DeRemee
Journal:  Otolaryngol Head Neck Surg (1979)       Date:  1980 Sep-Oct

7.  Hearing loss as the presenting feature of systemic vasculitis.

Authors:  Merav Lidar; Eldar Carmel; Yona Kronenberg; Pnina Langevitz
Journal:  Ann N Y Acad Sci       Date:  2007-06       Impact factor: 5.691

Review 8.  Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.

Authors:  A S Fauci; B F Haynes; P Katz; S M Wolff
Journal:  Ann Intern Med       Date:  1983-01       Impact factor: 25.391

9.  Prevalence and incidence of Wegener's granulomatosis in the UK general practice research database.

Authors:  Richard A Watts; Abdullah Al-Taiar; David G I Scott; Alex J Macgregor
Journal:  Arthritis Rheum       Date:  2009-10-15

10.  Age-related variations in presentation and outcome in Wegener's granulomatosis.

Authors:  M Vassallo; R J Shepherd; P Iqbal; I Feehally
Journal:  J R Coll Physicians Lond       Date:  1997 Jul-Aug
  10 in total

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