Literature DB >> 22688478

Paraneoplastic hyperthyroidism.

Sibylle Kohler1, Oliver Tschopp, Emanuel Jacky, Christoph Schmid.   

Abstract

The authors describe a 31-year-old male with a metastatic germ cell tumour and massively elevated human chorionic gonadotrophin (HCG) levels who presented with hyperthyroidism. As HCG is structurally closely related to thyroid stimulating hormone (TSH), it can activate the TSH receptor; grossly elevated levels may result in hyperthyroidism. After initiation of chemotherapy, HCG levels decreased and hyperthyroidism resolved.

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Year:  2011        PMID： 22688478      PMCID： PMC3158351          DOI： 10.1136/bcr.04.2011.4163

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  7 in total

1.  METASTATIC EMBRYONAL CARCINOMA OF THE TESTIS ASSOCIATED WITH ELEVATED PLASMA TSH-LIKE ACTIVITY AND HYPERTHYROIDISM.

Authors:  N H STEIGBIGEL; J J OPPENHEIM; L M FISHMAN; P P CARBONE
Journal:  N Engl J Med       Date:  1964-08-13       Impact factor: 91.245

Review 2.  Clinical practice. Nausea and vomiting in pregnancy.

Authors:  Jennifer R Niebyl
Journal:  N Engl J Med       Date:  2010-10-14       Impact factor: 91.245

3.  Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin.

Authors:  P Rodien; C Brémont; M L Sanson; J Parma; J Van Sande; S Costagliola; J P Luton; G Vassart; L Duprez
Journal:  N Engl J Med       Date:  1998-12-17       Impact factor: 91.245

4.  Prevalence of paraneoplastic hyperthyroidism in patients with metastatic non-seminomatous germ-cell tumors.

Authors:  S F Oosting; E C de Haas; T P Links; D de Bruin; W J Sluiter; I J de Jong; H J Hoekstra; D T Sleijfer; J A Gietema
Journal:  Ann Oncol       Date:  2009-07-15       Impact factor: 32.976

5.  Hyperthyroidism in men with germ cell tumors and high levels of beta-human chorionic gonadotropin.

Authors:  S A Giralt; F Dexeus; R Amato; A Sella; C Logothetis
Journal:  Cancer       Date:  1992-03-01       Impact factor: 6.860

Review 6.  Thyrotropic action of human chorionic gonadotropin.

Authors:  M Yoshimura; J M Hershman
Journal:  Thyroid       Date:  1995-10       Impact factor: 6.568

Review 7.  Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid.

Authors:  Jerome M Hershman
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2004-06       Impact factor: 4.690
  7 in total
  2 in total

Review 1.  Testicular choriocarcinoma: a rare variant that requires a unique treatment approach.

Authors:  Matthew James Reilley; Lance C Pagliaro
Journal:  Curr Oncol Rep       Date:  2015-02       Impact factor: 5.075

Review 2.  Thyroid Allostasis-Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming.

Authors:  Apostolos Chatzitomaris; Rudolf Hoermann; John E Midgley; Steffen Hering; Aline Urban; Barbara Dietrich; Assjana Abood; Harald H Klein; Johannes W Dietrich
Journal:  Front Endocrinol (Lausanne)       Date:  2017-07-20       Impact factor: 5.555
  2 in total

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