| Literature DB >> 22687848 |
Yayoi Shimazu1, Eiko N Minakawa, Momoko Nishikori, Masafumi Ihara, Yuichiro Hashi, Hirofumi Matsuyama, Masakatsu Hishizawa, Sonoyo Yoshida, Toshiyuki Kitano, Tadakazu Kondo, Takayuki Ishikawa, Ryosuke Takahashi, Akifumi Takaori-Kondo.
Abstract
Paraneoplastic neurological disorders (PND) are neurological effects of malignancy that are recognized as immune-mediated disorders caused by aberrant expression of a tumor antigen that is normally expressed in the nervous system. We report a case of cerebellar ataxia which turned out to be paraneoplastic cerebellar degeneration, a subtype of PND that develops cerebellar symptoms, that was caused by follicular lymphoma. After chemotherapy, the patient attained sufficient improvement of cerebellar symptoms along with complete remission of lymphoma. Paraneoplastic cerebellar degeneration should be recognized as a rare complication of lymphoma as it is important to start proper treatment before the neurological symptoms become irreversible.Entities:
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Year: 2012 PMID: 22687848 DOI: 10.2169/internalmedicine.51.7019
Source DB: PubMed Journal: Intern Med ISSN: 0918-2918 Impact factor: 1.271