Literature DB >> 22687848

A case of follicular lymphoma associated with paraneoplastic cerebellar degeneration.

Yayoi Shimazu1, Eiko N Minakawa, Momoko Nishikori, Masafumi Ihara, Yuichiro Hashi, Hirofumi Matsuyama, Masakatsu Hishizawa, Sonoyo Yoshida, Toshiyuki Kitano, Tadakazu Kondo, Takayuki Ishikawa, Ryosuke Takahashi, Akifumi Takaori-Kondo.   

Abstract

Paraneoplastic neurological disorders (PND) are neurological effects of malignancy that are recognized as immune-mediated disorders caused by aberrant expression of a tumor antigen that is normally expressed in the nervous system. We report a case of cerebellar ataxia which turned out to be paraneoplastic cerebellar degeneration, a subtype of PND that develops cerebellar symptoms, that was caused by follicular lymphoma. After chemotherapy, the patient attained sufficient improvement of cerebellar symptoms along with complete remission of lymphoma. Paraneoplastic cerebellar degeneration should be recognized as a rare complication of lymphoma as it is important to start proper treatment before the neurological symptoms become irreversible.

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Year:  2012        PMID: 22687848     DOI: 10.2169/internalmedicine.51.7019

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  2 in total

1.  Paraneoplastic cerebellar degeneration in a patient with anaplastic non-Hodgkin's lymphoma.

Authors:  Nadir Khan
Journal:  BMJ Case Rep       Date:  2018-06-15

Review 2.  Paraneoplastic neurological syndromes in Hodgkin and non-Hodgkin lymphomas.

Authors:  Francesc Graus; Helena Ariño; Josep Dalmau
Journal:  Blood       Date:  2014-04-04       Impact factor: 22.113

  2 in total

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