Malignant nature of cardiac liposarcoma revealed by fluorine-18 fluorodeoxyglucose positron emission tomographic imaging.

Primary cardiac liposarcoma is very rare and usually asymptomatic. It is often diagnosed at an advanced or incurable stage without being presented in surgical operation. We report a man in his early sixties with primary cardiac liposarcoma originating from the ventricular septum. The malignant nature of the tumor was suspected by positron emission tomography using fluorine-18 fluorodeoxyglucose as the tracer. The final diagnosis was made histopathologically following surgery. Treatment with carbon ion radiotherapy was applied, but failed to induce tumor regression.