Literature DB >> 22687839

Huge pancreatic acinar cell carcinoma with high levels of AFP and fucosylated AFP (AFP-L3).

Atsushi Hiraoka1, Hiromasa Nakahara, Hideki Kawasaki, Yuko Shimizu, Satoshi Hidaka, Yusuke Imai, Hiroki Utsunomiya, Haruka Tatsukawa, Nayu Tazuya, Hiroka Yamago, Nobukazu Yorimitsu, Tetsuya Tanihira, Aki Hasebe, Yasunao Miyamoto, Tomoyuki Ninomiya, Masanori Abe, Yoichi Hiasa, Bunzo Matsuura, Morikazu Onji, Kojiro Michitaka.   

Abstract

A 25-year-old Japanese woman with a large abdominal tumor (10 cm in diameter) and high level of serum alpha-fetoprotein (AFP, 1,222.4 ng/mL) was introduced and admitted to our hospital in January 2011. Pre-operative imaging modalities could not identify the tumor origin. There was no chronic hepatic viral disease, however, the elevated level of fucosylated AFP (87.8%) and connection with the left hepatic lobe led us to diagnose the tumor as a hepatocellular carcinoma. Surgical resection was performed in February. Histological findings revealed a pancreatic acinar cell carcinoma (ACC). Herein, we provide details of this difficulty to diagnose a case of ACC.

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Year:  2012        PMID: 22687839     DOI: 10.2169/internalmedicine.51.6536

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  8 in total

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Authors:  Adeline Yang; Alison Patterson; Tara Pavlock; Kenneth S Chen; Jeffrey Gagan; Mark E Hatley; A Lindsay Frazier; James F Amatruda; Theodore W Laetsch; Dinesh Rakheja
Journal:  Pediatr Blood Cancer       Date:  2021-12-05       Impact factor: 3.838

Review 3.  Targeted proteomics for biomarker discovery and validation of hepatocellular carcinoma in hepatitis C infected patients.

Authors:  Gul M Mustafa; Denner Larry; John R Petersen; Cornelis J Elferink
Journal:  World J Hepatol       Date:  2015-06-08

4.  Response of germline BRCA2-mutated advanced pancreatic acinar cell carcinoma to olaparib: A case report.

Authors:  Mao Li; Yu Mou; Shengzhong Hou; Dan Cao; Ang Li
Journal:  Medicine (Baltimore)       Date:  2018-11       Impact factor: 1.889

5.  Acinar cell carcinoma of the pancreas: clinical and cytomorphologic characteristics.

Authors:  Adam D Toll; Ralph H Hruban; Syed Z Ali
Journal:  Korean J Pathol       Date:  2013-04-24

6.  Evaluation of plasma D-dimer for the diagnosis in Chinese patients with hepatocellular carcinoma: A meta-analysis.

Authors:  Ping Fang; Lijun Du; Decheng Cai
Journal:  Medicine (Baltimore)       Date:  2020-03       Impact factor: 1.817

7.  Hepatic inflammatory pseudotumor associated with primary biliary cholangitis and elevated alpha-fetoprotein lectin 3 fraction mimicking hepatocellular carcinoma.

Authors:  Sho Endo; Yusuke Watanabe; Yuji Abe; Tomohiko Shinkawa; Sadafumi Tamiya; Kazuyoshi Nishihara; Toru Nakano
Journal:  Surg Case Rep       Date:  2018-09-10

8.  A Diagnostic Analysis Workflow to Optimal Multiple Tumor Markers to Predict the Nonmetastatic Breast Cancer from Breast Lumps.

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Journal:  J Oncol       Date:  2021-07-08       Impact factor: 4.375

  8 in total

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