| Literature DB >> 22687796 |
Nobuhiro Ayuzawa1, Yoshifumi Ubara, Sumida Keiichi, Yamanouchi Masayuki, Eiko Hasegawa, Eriko Hiramatsu, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Masateru Kawabata, Kenichi Ohashi, Kennmei Takaichi.
Abstract
A 68-year-old Japanese woman with asthma of recent onset and a long history of membranous glomerulonephropathy (MN) was admitted because of multifocal pulmonary infiltrates, marked eosinophilia, mild renal dysfunction, a rash on her feet, and right median nerve paralysis. Although MPO- and PR3-ANCA were negative, skin biopsy demonstrated leukocytoclastic vasculitis and Churg-Strauss Syndrome (CSS) was diagnosed. She also had salivary gland swelling and a high serum IgG4 level. Renal biopsy revealed MN with eosinophil-rich tubulointerstitial nephropathy. Her symptoms resolved after the start of corticosteroid therapy. The present case shows that ANCA-negative CSS can have a clinical condition similar to IgG4-related kidney disease.Entities:
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Year: 2012 PMID： 22687796 DOI： 10.2169/internalmedicine.51.6074
Source DB: PubMed Journal: Intern Med ISSN： 0918-2918 Impact factor: 1.271