Literature DB >> 22687389

Workshop on laboratory protocol standards for the Molecular Methods Database.

Tomas Klingström1, Larissa Soldatova, Robert Stevens, T Erik Roos, Morris A Swertz, Kristian M Müller, Matúš Kalaš, Patrick Lambrix, Michael J Taussig, Jan-Eric Litton, Ulf Landegren, Erik Bongcam-Rudloff.   

Abstract

Management of data to produce scientific knowledge is a key challenge for biological research in the 21st century. Emerging high-throughput technologies allow life science researchers to produce big data at speeds and in amounts that were unthinkable just a few years ago. This places high demands on all aspects of the workflow: from data capture (including the experimental constraints of the experiment), analysis and preservation, to peer-reviewed publication of results. Failure to recognise the issues at each level can lead to serious conflicts and mistakes; research may then be compromised as a result of the publication of non-coherent protocols, or the misinterpretation of published data. In this report, we present the results from a workshop that was organised to create an ontological data-modelling framework for Laboratory Protocol Standards for the Molecular Methods Database (MolMeth). The workshop provided a set of short- and long-term goals for the MolMeth database, the most important being the decision to use the established EXACT description of biomedical ontologies as a starting point.
Copyright © 2012. Published by Elsevier B.V. All rights reserved.

Mesh:

Year:  2012        PMID: 22687389     DOI: 10.1016/j.nbt.2012.05.019

Source DB:  PubMed          Journal:  N Biotechnol        ISSN: 1871-6784            Impact factor:   5.079


  3 in total

Review 1.  A critical analysis of cancer biobank practices in relation to biospecimen quality.

Authors:  Amanda Rush; Kevin Spring; Jennifer A Byrne
Journal:  Biophys Rev       Date:  2015-10-22

Review 2.  Toward a Literature-Driven Definition of Big Data in Healthcare.

Authors:  Emilie Baro; Samuel Degoul; Régis Beuscart; Emmanuel Chazard
Journal:  Biomed Res Int       Date:  2015-06-02       Impact factor: 3.411

3.  EXACT2: the semantics of biomedical protocols.

Authors:  Larisa N Soldatova; Daniel Nadis; Ross D King; Piyali S Basu; Emma Haddi; Véronique Baumlé; Nigel J Saunders; Wolfgang Marwan; Brian B Rudkin
Journal:  BMC Bioinformatics       Date:  2014-11-27       Impact factor: 3.169

  3 in total

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