| Literature DB >> 226870 |
H E Varmus, G Ringold, K R Yamamoto.
Abstract
Several laboratories have documented that glucocorticoid hormones markedly stimulate the expression of mouse mammary tumor virus genes in a variety of mouse mammary tumor cells and in infected heterologous cells. The effect of the hormone appears to be a rapid and specific augmentation of the synthesis of viral RNA, mediated by interaction with glucocorticoid receptor proteins. The availability of virus-specific reagents and recent developments in the molecular biology of RNA tumor viruses now permit a highly refined analysis of hormonal regulation in this experimental system.Entities:
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Year: 1979 PMID: 226870 DOI: 10.1007/978-3-642-81265-1_14
Source DB: PubMed Journal: Monogr Endocrinol ISSN: 0077-1015