Yan Hong1, Xia Huang, Hua Ling, Hongwen Liao. 1. Department of Social and Behavioral Health, School of Rural Public Health, Texas A&M Health Science Center, College Station, TX 77843, USA. yhong@srph.tamhsc.edu
Abstract
OBJECTIVE: In 1998, the Blood Donation Law was enacted in China in response to the outbreak of HIV endemic in central rural China as a result of unhygienic and commercial blood collection. This study aims to provide a first comprehensive review of available data on the prevalence, trend and other epidemiological characteristics of HIV infection among voluntary blood donors since 1998. METHODS: Major English and Chinese databases were searched and a systematic review was constructed. Pooled infection rates by province and year were calculated using random-effect or fixed-effect models. RESULTS: A total of 87 studies met our inclusion criteria. A total of 2573 HIV-positive cases were identified among voluntary blood donors in the past 10 years; the pooled prevalence was 13.22/100,000, with a range of 0.74-125.97 per 100,000. Among the 24 provinces that reported yearly data, the prevalence of HIV increased from 5.62/100,000 to 28.90/100,000. The male-to-female ratio was 2.8; about 60% were below the age of 30 years. CONCLUSIONS: The prevalence of HIV in voluntary blood donors has risen steadily and fast. Efficient measures need to be taken urgently to prevent HIV test-seeking through blood donor programmes, to promote voluntary blood donation in low-risk groups and to enforce the Blood Donation Law strictly.
OBJECTIVE: In 1998, the Blood Donation Law was enacted in China in response to the outbreak of HIV endemic in central rural China as a result of unhygienic and commercial blood collection. This study aims to provide a first comprehensive review of available data on the prevalence, trend and other epidemiological characteristics of HIV infection among voluntary blood donors since 1998. METHODS: Major English and Chinese databases were searched and a systematic review was constructed. Pooled infection rates by province and year were calculated using random-effect or fixed-effect models. RESULTS: A total of 87 studies met our inclusion criteria. A total of 2573 HIV-positive cases were identified among voluntary blood donors in the past 10 years; the pooled prevalence was 13.22/100,000, with a range of 0.74-125.97 per 100,000. Among the 24 provinces that reported yearly data, the prevalence of HIV increased from 5.62/100,000 to 28.90/100,000. The male-to-female ratio was 2.8; about 60% were below the age of 30 years. CONCLUSIONS: The prevalence of HIV in voluntary blood donors has risen steadily and fast. Efficient measures need to be taken urgently to prevent HIV test-seeking through blood donor programmes, to promote voluntary blood donation in low-risk groups and to enforce the Blood Donation Law strictly.
Authors: Roberta Bruhn; Elizabeth Moreno; Ester C Sabino; Naura Aparecida F Ferreira; Anna Barbara F Carneiro-Proietti; Maria Esther D Lopes; Divaldo Sampaio; Paula Loureiro; Brian Custer; Thelma T Goncalez Journal: Transfusion Date: 2016-09-09 Impact factor: 3.157
Authors: Chris Beyrer; Stefan D Baral; Brian W Weir; James W Curran; Richard E Chaisson; Patrick S Sullivan Journal: Curr Opin HIV AIDS Date: 2014-03 Impact factor: 4.283
Authors: Elizabeth C Moreno; Roberta Bruhn; Ester C Sabino; Eduarda Bolina-Santos; Carolina Miranda; Anna Barbara Carneiro-Proietti; Maria Esther Lopes; Cesar de Almeida-Neto; Paula Loureiro; Ligia Capuani; Pedro L Takecian; Brian Custer; Thelma T Gonçalez Journal: Hematol Transfus Cell Ther Date: 2019-02-18