Primary thyroid lymphoma in childhood: treatment with chemotherapy alone.

A 7-year-old boy developed primary non-Hodgkin's lymphoma (NHL) localized to the thyroid gland and was treated with combination chemotherapy alone. He has been continuously disease-free for 5 years since diagnosis, and is probably cured, without evidence of hypothyroidism or other unwanted late sequelae of external beam irradiation. Chemotherapy, alone, should be considered for the treatment of most, if not all, cases of localized NHL in childhood.