Literature DB >> 22684680

Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance.

David Alcantara1, Yanyan Guo, Hushan Yuan, Craig J Goergen, Howard H Chen, Hoonsung Cho, David E Sosnovik, Lee Josephson.   

Abstract

Easy to find: magnetic nanoparticles bearing fluorochromes (red) that intercalate with DNA (green) form microaggregates with DNA generated by the polymerase chain reaction (PCR). These aggregates can be detected at low cycle numbers by magnetic resonance (MR).
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 22684680      PMCID: PMC3477829          DOI: 10.1002/anie.201201661

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  27 in total

1.  A theoretical and experimental study of two thiazole orange derivatives with single- and double-stranded oligonucleotides, polydeoxyribonucleotides and DNA.

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2.  On T2-shortening by weakly magnetized particles: the chemical exchange model.

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3.  Magnetic relaxation switches capable of sensing molecular interactions.

Authors:  J Manuel Perez; Lee Josephson; Terrence O'Loughlin; Dagmar Högemann; Ralph Weissleder
Journal:  Nat Biotechnol       Date:  2002-07-22       Impact factor: 54.908

Review 4.  Stable dye-DNA intercalation complexes as reagents for high-sensitivity fluorescence detection.

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Journal:  Nature       Date:  1992-10-29       Impact factor: 49.962

5.  Use of magnetic nanoparticles as nanosensors to probe for molecular interactions.

Authors:  J Manuel Perez; Lee Josephson; Ralph Weissleder
Journal:  Chembiochem       Date:  2004-03-05       Impact factor: 3.164

6.  Measuring reaction kinetics in a lab-on-a-chip by microcoil NMR.

Authors:  Henk Wensink; Fernando Benito-Lopez; Dorothee C Hermes; Willem Verboom; Han J G E Gardeniers; David N Reinhoudt; Albert van den Berg
Journal:  Lab Chip       Date:  2005-01-28       Impact factor: 6.799

7.  Rapid and simple method for purification of nucleic acids.

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Journal:  J Clin Microbiol       Date:  1990-03       Impact factor: 5.948

8.  First-pass contrast-enhanced magnetic resonance angiography in humans using ferumoxytol, a novel ultrasmall superparamagnetic iron oxide (USPIO)-based blood pool agent.

Authors:  Wei Li; Sean Tutton; Anthony T Vu; Linda Pierchala; Belinda S Y Li; Jerome M Lewis; Pottumarthi V Prasad; Robert R Edelman
Journal:  J Magn Reson Imaging       Date:  2005-01       Impact factor: 4.813

9.  Sequence-specific DNA purification by triplex affinity capture.

Authors:  T Ito; C L Smith; C R Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-15       Impact factor: 11.205

10.  Oligonucleotide-modified gold nanoparticles for intracellular gene regulation.

Authors:  Nathaniel L Rosi; David A Giljohann; C Shad Thaxton; Abigail K R Lytton-Jean; Min Su Han; Chad A Mirkin
Journal:  Science       Date:  2006-05-19       Impact factor: 47.728

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  8 in total

1.  Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems.

Authors:  Hoonsung Cho; David Alcantara; Hushan Yuan; Rahul A Sheth; Howard H Chen; Peng Huang; Sean B Andersson; David E Sosnovik; Umar Mahmood; Lee Josephson
Journal:  ACS Nano       Date:  2013-02-07       Impact factor: 15.881

2.  Cytoprotective nanoparticles by conjugation of a polyhis tagged annexin V to a nanoparticle drug.

Authors:  Howard H Chen; Hushan Yuan; Hoonsung Cho; David E Sosnovik; Lee Josephson
Journal:  Nanoscale       Date:  2015-02-14       Impact factor: 7.790

3.  Heat-induced radiolabeling and fluorescence labeling of Feraheme nanoparticles for PET/SPECT imaging and flow cytometry.

Authors:  Hushan Yuan; Moses Q Wilks; Marc D Normandin; Georges El Fakhri; Charalambos Kaittanis; Lee Josephson
Journal:  Nat Protoc       Date:  2018-01-25       Impact factor: 13.491

Review 4.  Imaging DNA with fluorochrome bearing metals.

Authors:  Hoonsung Cho; Yanyan Guo; David E Sosnovik; Lee Josephson
Journal:  Inorg Chem       Date:  2013-05-06       Impact factor: 5.165

Review 5.  Homogeneous Biosensing Based on Magnetic Particle Labels.

Authors:  Stefan Schrittwieser; Beatriz Pelaz; Wolfgang J Parak; Sergio Lentijo-Mozo; Katerina Soulantica; Jan Dieckhoff; Frank Ludwig; Annegret Guenther; Andreas Tschöpe; Joerg Schotter
Journal:  Sensors (Basel)       Date:  2016-06-06       Impact factor: 3.576

6.  Cyclodextrin-Based Metal-Organic Nanotube as Fluorescent Probe for Selective Turn-On Detection of Hydrogen Sulfide in Living Cells Based on H2S-Involved Coordination Mechanism.

Authors:  Xuelian Xin; Jingxin Wang; Chuanfang Gong; Hai Xu; Rongming Wang; Shijie Ji; Hanxiao Dong; Qingguo Meng; Liangliang Zhang; Fangna Dai; Daofeng Sun
Journal:  Sci Rep       Date:  2016-02-25       Impact factor: 4.379

7.  Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials.

Authors:  Hushan Yuan; Moses Q Wilks; Georges El Fakhri; Marc D Normandin; Charalambos Kaittanis; Lee Josephson
Journal:  PLoS One       Date:  2017-02-22       Impact factor: 3.240

Review 8.  Luminophore and Magnetic Multicore Nanoassemblies for Dual-Mode MRI and Fluorescence Imaging.

Authors:  Lénaïc Lartigue; Marina Coupeau; Mélanie Lesault
Journal:  Nanomaterials (Basel)       Date:  2019-12-20       Impact factor: 5.076

  8 in total

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