Literature DB >> 22684421

Enantioselective synthesis of 3,3'-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction.

Wen-Tao Wei1, Chun-Xia Chen, Rui-Jiong Lu, Jin-Jia Wang, Xue-Jing Zhang, Ming Yan.   

Abstract

An organocatalytic three-component reaction of isatins, malononitrile and isocyanoacetates provided 3,3'-dihydropyrryl-spirooxindoles in excellent yields and enantioselectivities. The products could be readily converted to valuable 3,3'-pyrrolidinyl-spirooxindoles.

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Year:  2012        PMID： 22684421     DOI： 10.1039/c2ob25629k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

1.  Stereoselective syntheses of functionalized spirocyclopenteneoxindoles via triphenylphosphine-catalyzed [3+2] cycloaddition reactions.

Authors:  Qing-Fa Zhou; Xue-Ping Chu; Fei-Fei Ge; Cheng Li; Tao Lu
Journal:  Mol Divers       Date:  2013-06-19       Impact factor: 2.943

2.  Primary-tertiary diamine-catalyzed Michael addition of ketones to isatylidenemalononitrile derivatives.

Authors:  Akshay Kumar; Swapandeep Singh Chimni
Journal:  Beilstein J Org Chem       Date:  2014-04-24       Impact factor: 2.883
  2 in total

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