| Literature DB >> 22682238 |
Sakari Vanharanta1, Joan Massagué.
Abstract
Mutations in keratinocyte and melanocyte precursors that are caused by extensive sun exposure are well-established contributors to skin cancer. Now Hu et al. provide evidence that the sun's harmful rays may also cause tumor-promoting epigenetic modifications in dermal fibroblasts, highlighting further the importance of tumor-stroma interactions in cancer.Entities:
Year: 2012 PMID: 22682238 DOI: 10.1016/j.cell.2012.05.013
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582