Literature DB >> 22681682

Pharmacogenomics and personalized medicine in neuropsychiatry.

Francis J McMahon1, Thomas R Insel.   

Abstract

Despite the need for more effective treatments for psychiatric disorders, development of new medications has stalled. Here we discuss the promise of personalized medicine in developing more efficacious and individualized pharmacotherapies that take into account genetic variation and target groups of patients who share biology, not just symptoms.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22681682      PMCID: PMC3407812          DOI: 10.1016/j.neuron.2012.05.004

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  19 in total

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  22 in total

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Review 6.  Different Paths to Core Pathology: The Equifinal Model of the Schizophrenia Syndrome.

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7.  Genetic variation (CHRNA5), medication (combination nicotine replacement therapy vs. varenicline), and smoking cessation.

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Review 9.  Patient heal thyself: modeling and treating neurological disorders using patient-derived stem cells.

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Review 10.  Leveraging Genomic Data in Smoking Cessation Trials in the Era of Precision Medicine: Why and How.

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