Scaling laws for the response of nonlinear elastic media with implications for cell mechanics.

We show how strain stiffening affects the elastic response to internal forces, caused either by material defects and inhomogeneities or by active forces that molecular motors generate in living cells. For a spherical force dipole in a material with a strongly nonlinear strain energy density, strains change sign with distance, indicating that, even around a contractile inclusion or molecular motor, there is radial compression; it is only at a long distance that one recovers the linear response in which the medium is radially stretched. Scaling laws with irrational exponents relate the far-field renormalized strain to the near-field strain applied by the inclusion or active force.