| Literature DB >> 22680304 |
Yanala Sandeep Reddy1, Shaik Abbdul Nabi, Chippada Apparao, Chinthamaneni Srilatha, Yadla Manjusha, Parvathina Sri Ram Naveen, Chennu Krishna Kishore, Anappindi Sridhar, Vishnubotla Siva Kumar.
Abstract
We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats the renal lesions were noted in all and they were glomerular congestion, intertubular (interstitial) hemorrhages, acute tubular necrosis, mesangial proliferation, and intratubular casts. The severity of renal injury appears to be dose dependent.Entities:
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Year: 2012 PMID： 22680304 DOI： 10.3109/0886022X.2012.687346
Source DB: PubMed Journal: Ren Fail ISSN： 0886-022X Impact factor: 2.606