| Literature DB >> 22676237 |
Nohyun Lee1, Hye Rim Cho, Myoung Hwan Oh, Soo Hong Lee, Kangmin Kim, Byung Hyo Kim, Kwangsoo Shin, Tae-Young Ahn, Jin Woo Choi, Young-Woon Kim, Seung Hong Choi, Taeghwan Hyeon.
Abstract
Multimodal imaging is highly desirable for accurate diagnosis because it can provide complementary information from each imaging modality. In this study, a sol-gel reaction of tantalum(V) ethoxide in a microemulsion containing Fe(3)O(4) nanoparticles (NPs) was used to synthesize multifunctional Fe(3)O(4)/TaO(x) core/shell NPs, which were biocompatible and exhibited a prolonged circulation time. When the NPs were intravenously injected, the tumor-associated vessel was observed using computed tomography (CT), and magnetic resonance imaging (MRI) revealed the high and low vascular regions of the tumor.Entities:
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Year: 2012 PMID： 22676237 DOI： 10.1021/ja3016582
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419