Literature DB >> 22675147

Massive calcium channel blocker overdose: intravenous insulin and glucose as a therapy.

Gareth Rosser1, Simon William Dubrey.   

Abstract

We describe a case of massive overdosage with cardiac medications that proved resistant to conventional support, including fluid replacement, inotropes, mechanical ventilation, cardiac pacing and haemofiltration. The use of a high-dose insulin and glucose infusion proved to be beneficial in the acute management although the patient has been left with significant impairment of cardiac function.

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Year:  2012        PMID: 22675147      PMCID: PMC4543241          DOI: 10.1136/bcr.03.2012.6114

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

Review 1.  High-dose insulin therapy for calcium-channel blocker overdose.

Authors:  Greene Shepherd; Wendy Klein-Schwartz
Journal:  Ann Pharmacother       Date:  2005-04-05       Impact factor: 3.154

2.  Severe cardiac, respiratory, and metabolic complications of massive verapamil overdose.

Authors:  Z Quezado; M Lippmann; J Wertheimer
Journal:  Crit Care Med       Date:  1991-03       Impact factor: 7.598

3.  Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose.

Authors:  Deborah French; Patil Armenian; Weiming Ruan; Alicia Wong; Kenneth Drasner; Kent R Olson; Alan H B Wu
Journal:  Clin Toxicol (Phila)       Date:  2011-04       Impact factor: 4.467

Review 4.  High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning.

Authors:  Kristin M Engebretsen; Kathleen M Kaczmarek; Jenifer Morgan; Joel S Holger
Journal:  Clin Toxicol (Phila)       Date:  2011-04       Impact factor: 4.467

5.  Fatal verapamil overdose.

Authors:  G M Orr; H J Bodansky; D S Dymond; M Taylor
Journal:  Lancet       Date:  1982-11-27       Impact factor: 79.321

6.  Treating overdose with calcium channel blockers.

Authors:  J Kenny
Journal:  BMJ       Date:  1994-04-16

7.  Overdose with calcium channel blockers.

Authors:  N A Buckley; I M Whyte; A H Dawson
Journal:  BMJ       Date:  1994-06-18

Review 8.  The actions of insulin on cardiac contractility.

Authors:  A E Farah; A A Alousi
Journal:  Life Sci       Date:  1981-09-07       Impact factor: 5.037

Review 9.  Pharmacology, pathophysiology and management of calcium channel blocker and beta-blocker toxicity.

Authors:  Christopher R DeWitt; Javier C Waksman
Journal:  Toxicol Rev       Date:  2004

10.  Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.

Authors:  Tero Varpula; Janne Rapola; Marko Sallisalmi; Jouni Kurola
Journal:  Anesth Analg       Date:  2009-03       Impact factor: 5.108

  10 in total
  1 in total

Review 1.  Treatment for calcium channel blocker poisoning: a systematic review.

Authors:  M St-Onge; P-A Dubé; S Gosselin; C Guimont; J Godwin; P M Archambault; J-M Chauny; A J Frenette; M Darveau; N Le Sage; J Poitras; J Provencher; D N Juurlink; R Blais
Journal:  Clin Toxicol (Phila)       Date:  2014-10-06       Impact factor: 4.467

  1 in total

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