Literature DB >> 22675099

Do not forget about HELLP!

Michael Bennett1.   

Abstract

A 32-year-old female para 4 gravi 3, who was 21 weeks pregnant, presented to the emergency department (ED) with a 2-day history of abdominal pain, headache, blurred vision and vomiting. On arrival, she was agitated and confused with a blood pressure 162/106 mm Hg, pulse rate 107, respiratory rate 18, temperature 37 degrees Celsius, point of care blood glucose 6.2 and her Glasgow coma scale was 13/15 M6V4E3. Paramedics witnessed seizure-like activity lasting <1 min during transport. A diagnosis of eclampsia complicated by the HELLP syndrome (haemolysis, elevated liver enzymes, low platelets count) was made. She was commenced on magnesium and labetalol intravenously for blood pressure control. Initial blood test results were consistent with the HELLP syndrome. Recognition of the HELLP syndrome with prompt management of blood pressure and clotting abnormalities is essential in the ED setting. An aggressive multidisciplinary approach is a key to optimise the prognosis for mother and fetus.

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Year:  2011        PMID: 22675099      PMCID: PMC3207765          DOI: 10.1136/bcr.08.2011.4693

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

Review 1.  Pathogenesis of preeclampsia: a comprehensive model.

Authors:  E van Beck; L L Peeters
Journal:  Obstet Gynecol Surv       Date:  1998-04       Impact factor: 2.347

2.  Temporising management of severe pre-eclampsia with and without the HELLP syndrome.

Authors:  W Visser; H C Wallenburg
Journal:  Br J Obstet Gynaecol       Date:  1995-02

3.  Maternal-perinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia-eclampsia.

Authors:  B M Sibai; M M Taslimi; A el-Nazer; E Amon; B C Mabie; G M Ryan
Journal:  Am J Obstet Gynecol       Date:  1986-09       Impact factor: 8.661

4.  Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

Authors:  B M Sibai; M K Ramadan; I Usta; M Salama; B M Mercer; S A Friedman
Journal:  Am J Obstet Gynecol       Date:  1993-10       Impact factor: 8.661

5.  Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy.

Authors:  L Weinstein
Journal:  Am J Obstet Gynecol       Date:  1982-01-15       Impact factor: 8.661

  5 in total

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