Literature DB >> 22674593

Fusobacterium necrophorum--beyond Lemierres syndrome.

Lokesh Shahani1, Nancy Khardori.   

Abstract

Fusobacterium necrophorum is a non-sporulating anaerobic gram negative bacillus and has traditionally been associated with Lemierre's syndrome. The authors report a 34-year-old male who presented to the emergency department with a week's history of dull epigastirc pain. Significant medical history included chronic pancreatitis secondary to alcohol use. The patient had radiological evidence of acute on chronic pancreatitis with thrombosis of the portal vein and multiple intrahepatic abscesses. CT-guided drainage of left upper quadrant revealed fluid collection in the pancreatic bed. The fluid culture grew F necrophorum and the patient was treated with tigecycline for 4 weeks. The patient improved symptomatically and his follow-up computerised axial tomography scan 2 months later showed resolving liver abscess, cavernous transformation of the portal vein and stable findings of chronic pancreatitis. This could represent an infection of the peripancreatic tissue with F necrophorum further leading to pylephlebitis.

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Year:  2011        PMID: 22674593      PMCID: PMC3229337          DOI: 10.1136/bcr.07.2011.4527

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Fusobacterium nucleatum septicemia and portal vein thrombosis.

Authors:  I E Bultink; J W Dorigo-Zetsma; M G Koopman; E J Kuijper
Journal:  Clin Infect Dis       Date:  1999-06       Impact factor: 9.079

2.  Septic portal vein thrombosis due to Fusobacterium necrophorum.

Authors:  R Soo; I Gosbell; J Gallo; C S Pokorny
Journal:  Aust N Z J Med       Date:  1999-08

3.  Fusobacterium nucleatum hepatic abscess with pylephlebitis associated with idiopathic CD4(+) T lymphocytopenia.

Authors:  M Etienne; I Gueit; P Abboud; J L Pons; S Jacquot; F Caron
Journal:  Clin Infect Dis       Date:  2001-01-15       Impact factor: 9.079

4.  Portal vein thrombosis associated with Fusobacterium nucleatum septicemia in a patient with ulcerative colitis.

Authors:  Elizabeth C Verna; Alberto Larghi; Sami G Faddoul; Jeffrey A Stein; Howard J Worman
Journal:  J Clin Gastroenterol       Date:  2004-08       Impact factor: 3.062

Review 5.  The evolution of Lemierre syndrome: report of 2 cases and review of the literature.

Authors:  Julio A Chirinos; Daniel M Lichtstein; Javier Garcia; Leonardo J Tamariz
Journal:  Medicine (Baltimore)       Date:  2002-11       Impact factor: 1.889

Review 6.  Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era.

Authors:  R M Plemmons; D P Dooley; R N Longfield
Journal:  Clin Infect Dis       Date:  1995-11       Impact factor: 9.079

Review 7.  Mesenteric adenitis and portal vein thrombosis due to Fusobacterium nucleatum.

Authors:  Roland El Braks; Florence Harnois; Nevine Boutros; David Fallik; Jean Roudie; Claude Smadja; Jocelyne De Laveaucoupet; Jean-Claude Chaput; Sylvie Naveau; Philippe Mathurin
Journal:  Eur J Gastroenterol Hepatol       Date:  2004-10       Impact factor: 2.566

8.  Aggregation of platelets by Fusobacterium necrophorum.

Authors:  L J Forrester; B J Campbell; J N Berg; J T Barrett
Journal:  J Clin Microbiol       Date:  1985-08       Impact factor: 5.948

  8 in total
  9 in total

1.  Fusobacterium nucleatum as a prognostic marker of colorectal cancer in a Japanese population.

Authors:  Yuko Yamaoka; Yutaka Suehiro; Shinichi Hashimoto; Tomomi Hoshida; Michiyo Fujimoto; Michiya Watanabe; Daiki Imanaga; Kouhei Sakai; Toshihiko Matsumoto; Mitsuaki Nishioka; Taro Takami; Nobuaki Suzuki; Shoichi Hazama; Hiroaki Nagano; Isao Sakaida; Takahiro Yamasaki
Journal:  J Gastroenterol       Date:  2017-08-19       Impact factor: 7.527

Review 2.  Role of the microbiome in non-gastrointestinal cancers.

Authors:  Meirav Pevsner-Fischer; Timur Tuganbaev; Mariska Meijer; Sheng-Hong Zhang; Zhi-Rong Zeng; Min-Hu Chen; Eran Elinav
Journal:  World J Clin Oncol       Date:  2016-04-10

Review 3.  Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.

Authors:  Katsuhiko Nosho; Yasutaka Sukawa; Yasushi Adachi; Miki Ito; Kei Mitsuhashi; Hiroyoshi Kurihara; Shinichi Kanno; Itaru Yamamoto; Keisuke Ishigami; Hisayoshi Igarashi; Reo Maruyama; Kohzoh Imai; Hiroyuki Yamamoto; Yasuhisa Shinomura
Journal:  World J Gastroenterol       Date:  2016-01-14       Impact factor: 5.742

4.  Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.

Authors:  Kei Mitsuhashi; Katsuhiko Nosho; Yasutaka Sukawa; Yasutaka Matsunaga; Miki Ito; Hiroyoshi Kurihara; Shinichi Kanno; Hisayoshi Igarashi; Takafumi Naito; Yasushi Adachi; Mami Tachibana; Tokuma Tanuma; Hiroyuki Maguchi; Toshiya Shinohara; Tadashi Hasegawa; Masafumi Imamura; Yasutoshi Kimura; Koichi Hirata; Reo Maruyama; Hiromu Suzuki; Kohzoh Imai; Hiroyuki Yamamoto; Yasuhisa Shinomura
Journal:  Oncotarget       Date:  2015-03-30

Review 5.  Fusobacterial liver abscess: a case report and review of the literature.

Authors:  Dilip Jayasimhan; Linus Wu; Paul Huggan
Journal:  BMC Infect Dis       Date:  2017-06-20       Impact factor: 3.090

6.  Melioidosis with Portal Vein Thrombosis.

Authors:  Thanyaporn Direksunthorn
Journal:  Case Rep Infect Dis       Date:  2017-04-03

Review 7.  Suppurative Thrombosis of the Portal Vein (Pylephlebits): A Systematic Review of Literature.

Authors:  Dorde Jevtic; Tatjana Gavrancic; Ivana Pantic; Terri Nordin; Charles W Nordstrom; Marina Antic; Nikola Pantic; Marija Kaljevic; Bojan Joksimovic; Milan Jovanovic; Emilia Petcu; Mladen Jecmenica; Tamara Milovanovic; Lawrence Sprecher; Igor Dumic
Journal:  J Clin Med       Date:  2022-08-25       Impact factor: 4.964

8.  Pancreatitis in tigecycline Phase 3 and 4 clinical studies.

Authors:  Paul C McGovern; Michele Wible; Joan M Korth-Bradley; Alvaro Quintana
Journal:  J Antimicrob Chemother       Date:  2013-11-11       Impact factor: 5.790

9.  Late presentation of 'Lemierre's syndrome': how a delay in seeking healthcare and reduced access to routine services resulted in widely disseminated Fusobacterium necrophorum infection during the global COVID-19 pandemic.

Authors:  Fergal Howley; Laura O'Doherty; Niall McEniff; Ruth O'Riordan
Journal:  BMJ Case Rep       Date:  2020-10-10
  9 in total

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