Literature DB >> 22674080

Adherens junctions and cancer.

Valeri Vasioukhin1.   

Abstract

Cadherins and catenins are the central cell-cell adhesion molecules in adherens junctions (AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in epithelial cancer and examines the published literature demonstrating the changes in the expression and function of these proteins in human cancer and the association of these changes with patient outcomes. The chapter also covers the mechanistic studies aiming at uncovering the significance of changes in cadherin and catenin expression in cancer and potential molecular mechanisms responsible for the causal role of AJs in cancer initiation and progression.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22674080     DOI： 10.1007/978-94-007-4186-7_16

Source DB:  PubMed          Journal:  Subcell Biochem        ISSN： 0306-0225


  24 in total

1.  E-cadherin junction formation involves an active kinetic nucleation process.

Authors:  Kabir H Biswas; Kevin L Hartman; Cheng-han Yu; Oliver J Harrison; Hang Song; Adam W Smith; William Y C Huang; Wan-Chen Lin; Zhenhuan Guo; Anup Padmanabhan; Sergey M Troyanovsky; Michael L Dustin; Lawrence Shapiro; Barry Honig; Ronen Zaidel-Bar; Jay T Groves
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-19       Impact factor: 11.205

2.  Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force.

Authors:  Kabir H Biswas; Kevin L Hartman; Ronen Zaidel-Bar; Jay T Groves
Journal:  Biophys J       Date:  2016-09-06       Impact factor: 4.033

3.  NCEH1 may be a prognostic biomarker for pancreatic cancer.

Authors:  Yan Lu; Longyi Zhang; Xuya Chen; Qiaohong Zhang
Journal:  Int J Clin Exp Pathol       Date:  2020-11-01

Review 4.  Control of cellular responses to mechanical cues through YAP/TAZ regulation.

Authors:  Ishani Dasgupta; Dannel McCollum
Journal:  J Biol Chem       Date:  2019-10-08       Impact factor: 5.157

5.  Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force.

Authors:  Craig D Buckley; Jiongyi Tan; Karen L Anderson; Dorit Hanein; Niels Volkmann; William I Weis; W James Nelson; Alexander R Dunn
Journal:  Science       Date:  2014-10-31       Impact factor: 47.728

6.  Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins.

Authors:  Robert F Hennigan; Jonathan S Fletcher; Steven Guard; Nancy Ratner
Journal:  Sci Signal       Date:  2019-04-23       Impact factor: 8.192

7.  Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadherin pathway in human hepatocellular cancer.

Authors:  Xiu-Lan Peng; Meng-Yao Ji; Zi-Rong Yang; Jia Song; Wei-Guo Dong
Journal:  World J Gastroenterol       Date:  2013-02-28       Impact factor: 5.742

8.  Characterization of Kinase Expression Related to Increased Migration of PC-3M Cells Using Global Comparative Phosphoproteome Analysis.

Authors:  Yan Gao; Yun-Sok Ha; Tae Gyun Kwon; Young-Chang Cho; Sangkyu Lee; Jun Nyung Lee
Journal:  Cancer Genomics Proteomics       Date:  2020 Sep-Oct       Impact factor: 4.069

Review 9.  p120catenin alteration in cancer and its role in tumour invasion.

Authors:  Florent Peglion; Sandrine Etienne-Manneville
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-09-23       Impact factor: 6.237

10.  Adherens junction distribution mechanisms during cell-cell contact elongation in Drosophila.

Authors:  Gabrielle Goldenberg; Tony J C Harris
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.