| Literature DB >> 22672535 |
A Xhaard1, F Lanternier, R Porcher, E Dannaoui, A Bergeron, L Clement, C Lacroix, R Herbrecht, F Legrand, M Mohty, M Michallet, C Cordonnier, S Malak, D Guyotat, L J Couderc, G Socié, N Milpied, O Lortholary, P Ribaud.
Abstract
We conducted a nationwide retrospective study to evaluate clinical characteristics and outcome of mucormycosis among allogeneic haematopoietic stem cell transplant recipients. Twenty-nine patients were diagnosed between 2003 and 2008. Mucormycosis occurred at a median of 225 days after allogeneic haematopoietic stem cell transplant, and as a breakthrough infection in 23 cases. Twenty-six patients were receiving steroids, mainly for graft-versus-host disease treatment, while ten had experienced a prior post-transplant invasive fungal infection. Twenty-six patients received an antifungal treatment; surgery was performed in 12. Overall survival was 34% at 3 months and 17% at 1 year.Entities:
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Year: 2012 PMID： 22672535 DOI： 10.1111/j.1469-0691.2012.03908.x
Source DB: PubMed Journal: Clin Microbiol Infect ISSN： 1198-743X Impact factor: 8.067