Literature DB >> 2267207

Withdrawal of maintenance digoxin from institutionalized elderly.

C Macarthur1.   

Abstract

Chronic use of digitalis is common amongst the institutionalized elderly. Associated with digitalis use is the potential for toxicity and/or adverse reactions. In this study maintenance digoxin was withdrawn from 14 elderly nursing home residents in sinus rhythm. Subjects were followed over 18 months for evidence of dysrhythmia or heart failure. One resident had an episode of supraventricular tachycardia which required digoxin to be restarted. One resident developed left heart failure, treated with oral diuretic. For 12 of the 14 residents, withdrawal of maintenance digoxin was achieved without deleterious effect. This study suggests that maintenance digoxin may be withdrawn safely in elderly nursing home residents in sinus rhythm and without history of atrial dysrhythmia.

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Year:  1990        PMID: 2267207      PMCID: PMC2429742          DOI: 10.1136/pgmj.66.781.940

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  18 in total

1.  Drug prescribing in hospitals: an international comparison.

Authors:  D H Lawson; H Jick
Journal:  Am J Public Health       Date:  1976-07       Impact factor: 9.308

2.  The efficacy of digitalis withdrawal in an institutional aged population.

Authors:  H A Fonrose; N Ahlbaum; E Bugatch; M Cohen; C Genovese; J Kelly
Journal:  J Am Geriatr Soc       Date:  1974-05       Impact factor: 5.562

3.  The natural history of congestive heart failure: the Framingham study.

Authors:  P A McKee; W P Castelli; P M McNamara; W B Kannel
Journal:  N Engl J Med       Date:  1971-12-23       Impact factor: 91.245

4.  Pharmacokinetics of digoxin in the elderly [proceedings].

Authors:  B Cusack; J Horgan; J G Kelly; J Lavan; J Noel; K O'Malley
Journal:  Br J Clin Pharmacol       Date:  1978-11       Impact factor: 4.335

5.  The paradox of the lack of the efficacy of digitalis in congestive heart failure with sinus rhythm.

Authors:  J Hamer
Journal:  Br J Clin Pharmacol       Date:  1979-08       Impact factor: 4.335

6.  Monitoring digoxin therapy in two long-term facilities.

Authors:  B L Carter; R E Small; W R Garnett
Journal:  J Am Geriatr Soc       Date:  1981-06       Impact factor: 5.562

7.  Is maintenance digoxin necessary in geriatric patients?

Authors:  K Boman; S Allgulander; M Skoglund
Journal:  Acta Med Scand       Date:  1981

8.  Effects of discontinuing maintenance digoxin therapy in patients with ischemic heart disease and congestive heart failure in sinus rhythm.

Authors:  M Gheorghiade; G A Beller
Journal:  Am J Cardiol       Date:  1983-05-01       Impact factor: 2.778

9.  Is maintenance digoxin necessary in patients with sinus rhythm?

Authors:  G D Johnston; D G McDevitt
Journal:  Lancet       Date:  1979-03-17       Impact factor: 79.321

10.  Digoxin withdrawal after cardiac failure in patients with sinus rhythm.

Authors:  A J Taggart; G D Johnston; D G McDevitt
Journal:  J Cardiovasc Pharmacol       Date:  1983 Mar-Apr       Impact factor: 3.105

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  3 in total

1.  Withdrawal of maintenance digoxin from institutionalized elderly.

Authors:  B J Liddle
Journal:  Postgrad Med J       Date:  1991-06       Impact factor: 2.401

2.  Chronic Digoxin Toxicity Leading to Institutionalization of an Elderly Woman.

Authors:  Kimberley Nix; Luiza Radu; Jason Zou; Meghan E O Vlasschaert
Journal:  Can J Hosp Pharm       Date:  2022-04-04

Review 3.  The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis.

Authors:  Amy T Page; Rhonda M Clifford; Kathleen Potter; Darren Schwartz; Christopher D Etherton-Beer
Journal:  Br J Clin Pharmacol       Date:  2016-06-13       Impact factor: 4.335

  3 in total

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