Literature DB >> 22671987

Bioactive sesquiterpenoids from the rhizomes of Acorus calamus.

Zhi-You Hao1, Dong Liang, Huan Luo, Yan-Fei Liu, Gang Ni, Qing-Jian Zhang, Li Li, Yi-Kang Si, Hua Sun, Ruo-Yun Chen, De-Quan Yu.   

Abstract

Eight new sesquiterpenes (1-8) and one new norsesquiterpene (9) named calamusins A-I were isolated from the ethanol extract of Acorus calamus rhizomes. The absolute configuration of compound 8 was determined by comparing its experimental and calculated ECD spectra. The absolute configurations of the other compounds were determined from their CD spectra. Furthermore, in in vitro assays, compounds 3, 4, 7, and 9 (10 μM) exhibited weak hepatoprotective activities against APAP-induced HepG2 cell damage.

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Year:  2012        PMID： 22671987     DOI： 10.1021/np300095c

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Anti-RAFLS Triterpenoids and Hepatoprotective Lignans From the Leaves of Tujia Ethnomedicine Kadsura heteroclita (Xuetong).

Authors:  Mengyun Wang; Sai Jiang; Nusrat Hussain; Salman Zafar; Qingling Xie; Feibing Huang; Linxi Mao; Bin Li; Yuqing Jian; Wei Wang
Journal:  Front Chem       Date:  2022-05-10       Impact factor: 5.545

2.  Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata.

Authors:  Chuangfeng Zhang; Jian Zhou; Jingzhi Yang; Chuangjun Li; Jie Ma; Dan Zhang; Dongming Zhang
Journal:  Acta Pharm Sin B       Date:  2016-06-17       Impact factor: 11.413

3.  1,3-Oxazin-6-one Derivatives and Bohemamine-Type Pyrrolizidine Alkaloids from a Marine-Derived Streptomyces spinoverrucosus.

Authors:  Peng Fu; Scott La; John B MacMillan
Journal:  J Nat Prod       Date:  2015-10-21       Impact factor: 4.050

4.  New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb.

Authors:  Jie Ma; Chuang-Jun Li; Jing-Zhi Yang; Hua Sun; Dong-Ming Zhang
Journal:  Molecules       Date:  2017-01-18       Impact factor: 4.411

5.  New Acorane-Type Sesquiterpene from Acorus calamus L.

Authors:  Juan Li; Jianping Zhao; Wei Wang; Lin Li; Lan Zhang; Xiao-Fang Zhao; Qing-Ru Liu; Fang Liu; Min Yang; Ikhlas A Khan; Shun-Xiang Li
Journal:  Molecules       Date:  2017-03-26       Impact factor: 4.411

Review 6.  Spirocyclic Motifs in Natural Products.

Authors:  Evgeny Chupakhin; Olga Babich; Alexander Prosekov; Lyudmila Asyakina; Mikhail Krasavin
Journal:  Molecules       Date:  2019-11-17       Impact factor: 4.411

7.  Bioactive Compounds from the Stems of Clausena lansium.

Authors:  Jie Liu; Chuang-Jun Li; Yi-Qian Du; Li Li; Hua Sun; Nai-Hong Chen; Dong-Ming Zhang
Journal:  Molecules       Date:  2017-12-14       Impact factor: 4.411

Review 8.  Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites.

Authors:  Víctor Coca-Ruíz; Ivonne Suárez; Josefina Aleu; Isidro G Collado
Journal:  Plants (Basel)       Date:  2022-03-14
  8 in total

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