Literature DB >> 22669995

Acute cardiogenic pulmonary oedema with multiorgan dysfunction--still to learn more about nitrobenzene poisoning.

Avinash Agrawal1, Manish Gutch, Rahul Arora, Nirdesh Jain.   

Abstract

Nitrobenzene is a nitrite compound often used in polishes or solvents. Its toxic effects are due to its ability to induce methaemoglobinaemia. The clinical presentation of this poisoning varies according to the concentration of methaemoglobin level in blood. The importance of early identification of the compound on the basis of clinical suspicion corroborative with methaemoglobin level with timely intervention is required to prevent fatal outcome. It is also important to take care of the secondary cycling of nitrobenzene from body stores to prevent secondary recurrence of symptoms in patients after heavy exposure. Here author reports a rare case of accidental poisoning with nitrobenzene presented with respiratory distress and cyanosis. On investigation, he was diagnosed to have cardiogenic pulmonary oedema and multiorgan dysfunction. The urgent institution of methylene blue as specific antidote along with haemodynamic and ventilatory support was proved crucial for life saving of the patient.

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Year:  2011        PMID: 22669995      PMCID: PMC3246171          DOI: 10.1136/bcr.10.2011.5026

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

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Authors:  G Gupta; B Poddar; M Salaria; V Parmar
Journal:  Indian Pediatr       Date:  2000-10       Impact factor: 1.411

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Journal:  Anesthesiology       Date:  1988-02       Impact factor: 7.892

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Authors:  D S Chongtham; J Phurailatpam; M M Singh; T R Singh
Journal:  J Postgrad Med       Date:  1997 Jul-Sep       Impact factor: 1.476

Review 4.  Methemoglobinemia: etiology, pharmacology, and clinical management.

Authors:  R O Wright; W J Lewander; A D Woolf
Journal:  Ann Emerg Med       Date:  1999-11       Impact factor: 5.721

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Authors:  S Curry
Journal:  Ann Emerg Med       Date:  1982-04       Impact factor: 5.721

6.  Celecoxib-induced methemoglobinemia.

Authors:  Prashant Kaushik; Steven J Zuckerman; Nicholas J Campo; Venkatramana R Banda; Scott D Hayes; Richa Kaushik
Journal:  Ann Pharmacother       Date:  2004-08-24       Impact factor: 3.154

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Authors:  A Mansouri
Journal:  Am J Med Sci       Date:  1985-05       Impact factor: 2.378

8.  Nitrite-induced methaemoglobinaemia.

Authors:  T Walley; M Flanagan
Journal:  Postgrad Med J       Date:  1987-08       Impact factor: 2.401

9.  Diagnostic efficiency of troponin T measurements in acute myocardial infarction.

Authors:  H A Katus; A Remppis; F J Neumann; T Scheffold; K W Diederich; G Vinar; A Noe; G Matern; W Kuebler
Journal:  Circulation       Date:  1991-03       Impact factor: 29.690

10.  Methemoglobinemia resulting from absorption of nitrates.

Authors:  J C Harris; B H Rumack; R G Peterson; B M McGuire
Journal:  JAMA       Date:  1979-12-28       Impact factor: 56.272

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