Literature DB >> 22669984

Scar sarcoidosis with bone marrow involvement and associated musculoskeletal symptoms.

Omair Akhtar Hameed1, Malgorzata Skibinska.   

Abstract

Sarcoidosis affects the lungs most commonly and can present with cutaneous lesions. It can also involve the bone marrow in rare instances, often presenting with non-specific symptoms such as fever and malaise, with occasional haematological abnormalities. The authors present the case of a 41-year-old caucasian female who was diagnosed with scar sarcoidosis, but who also reported fatigue, night sweats and polyarthralgia. No haematological abnormalities or lung involvement were detected. A magnetic resonance scan of the spine, performed due to disc prolapses, demonstrated areas of bone oedema and stress response that were reported as a possible sarcoid infiltration of the bone marrow. An improvement occurred after 8 weeks, despite conservative treatment. Bone marrow involvement in sarcoidosis is rarely reported, and was an accidental finding here. Due to the non-specific presentation, cases such as this are potentially underdiagnosed and should be considered in patients with systemic symptoms, regardless of their haematological status.

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Year:  2011        PMID: 22669984      PMCID: PMC3246150          DOI: 10.1136/bcr.02.2011.3863

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  Fever of unknown origin and isolated noncaseating granuloma of the marrow: could this be sarcoidosis?

Authors:  Andrew C Miller; Thomas Chacko; Rashid M Rashid; Dennis K Ledford
Journal:  Allergy Asthma Proc       Date:  2007 Mar-Apr       Impact factor: 2.587

Review 2.  Sarcoidosis.

Authors:  Owen J Dempsey; Edward W Paterson; Keith M Kerr; Alan R Denison
Journal:  BMJ       Date:  2009-08-28

3.  Bone marrow sarcoidosis.

Authors:  P M Browne; O P Sharma; D Salkin
Journal:  JAMA       Date:  1978-12-08       Impact factor: 56.272

Review 4.  Sarcoidosis.

Authors:  J C English; P J Patel; K E Greer
Journal:  J Am Acad Dermatol       Date:  2001-05       Impact factor: 11.527

5.  Reactivation of old scars: inevitably sarcoid.

Authors:  J S Sorabjee; R Garje
Journal:  Postgrad Med J       Date:  2005-01       Impact factor: 2.401

Review 6.  Chronic cutaneous lesions of sarcoidosis.

Authors:  Richard M Marchell; Marc A Judson
Journal:  Clin Dermatol       Date:  2007 May-Jun       Impact factor: 3.541

7.  Sarcoidosis of the thoracic and lumbar vertebrae, mimicking metastasis or multifocal osteomyelitis by MRI: case report.

Authors:  Maria P Valencia; Pamela M Deaver; Marisa C Mammarappallil
Journal:  Clin Imaging       Date:  2009 Nov-Dec       Impact factor: 1.605

8.  Sarcoidal anemia and leukopenia treated with methotrexate and mycophenolate mofetil.

Authors:  Andrew H Kalajian; Jonathan R Van Meter; Jeffrey P Callen
Journal:  Arch Dermatol       Date:  2009-08

Review 9.  Musculoskeletal sarcoidosis: spectrum of appearances at MR imaging.

Authors:  Sandra L Moore; Alvin E Teirstein
Journal:  Radiographics       Date:  2003 Nov-Dec       Impact factor: 5.333

  9 in total
  1 in total

1.  Sarcoidosis with Rare Extrapulmonary Involvement.

Authors:  Marta Brandão Calçada; Sara Montezinho; Andreia M Teixeira; Bruno Gomes; Bernardo Macedo
Journal:  Eur J Case Rep Intern Med       Date:  2021-07-12
  1 in total

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