BACKGROUND: Sickle cell disease (SCD) with its attendant increased energy requirements has an adverse effect on growth. Good nutrition is essential for normal childhood growth and development. Differences in growth between children living within the same SEC's are likely to be due to the effects of the sickle cell disease. OBJECTIVE: To determine the relationship between SCD and nutritional status in children. METHODS: This cross-sectional study, conducted at the Paediatric Sickle Cell Clinic of the Korle Bu Teaching Hospital, recruited 427 children aged 1-12 years: 357 SCD patients (cases) and 70 of their siblings with Hb AA (controls), over a four-month period. Their socio-demographic data, weight and height/length were documented, and the weight-for-age (WAZ) and height/length-for-age (HAZ), weight-for-height/length (WHZ) scores calculated as indices of nutritional status. RESULTS: The mean (SD) age of SCD participants was 7.18 (3.15) years and of controls was 5.13 (3.28) years, (p=0.8). The prevalence of malnutrition was 61.3% among SCD subjects and 28.6% among controls, (p<0.001). The WAZ (underweight) and HAZ (stunting) scores were significantly more common among SCD children than controls, but the difference in the rates of wasting (WHZ) was not significant (p=0.3). CONCLUSION: Ghanaian SCD children are more underweight and stunted than their Hb AA counterparts living under similar socio-economic conditions. Better education of families about the nutritional needs of SCD children in our community is needed.
BACKGROUND:Sickle cell disease (SCD) with its attendant increased energy requirements has an adverse effect on growth. Good nutrition is essential for normal childhood growth and development. Differences in growth between children living within the same SEC's are likely to be due to the effects of the sickle cell disease. OBJECTIVE: To determine the relationship between SCD and nutritional status in children. METHODS: This cross-sectional study, conducted at the Paediatric Sickle Cell Clinic of the Korle Bu Teaching Hospital, recruited 427 children aged 1-12 years: 357 SCDpatients (cases) and 70 of their siblings with Hb AA (controls), over a four-month period. Their socio-demographic data, weight and height/length were documented, and the weight-for-age (WAZ) and height/length-for-age (HAZ), weight-for-height/length (WHZ) scores calculated as indices of nutritional status. RESULTS: The mean (SD) age of SCDparticipants was 7.18 (3.15) years and of controls was 5.13 (3.28) years, (p=0.8). The prevalence of malnutrition was 61.3% among SCD subjects and 28.6% among controls, (p<0.001). The WAZ (underweight) and HAZ (stunting) scores were significantly more common among SCDchildren than controls, but the difference in the rates of wasting (WHZ) was not significant (p=0.3). CONCLUSION: Ghanaian SCDchildren are more underweight and stunted than their Hb AA counterparts living under similar socio-economic conditions. Better education of families about the nutritional needs of SCDchildren in our community is needed.
Authors: Olubusola B Oluwole; Robert B Noll; Daniel G Winger; Olu Akinyanju; Enrico M Novelli Journal: Pediatr Blood Cancer Date: 2016-07-09 Impact factor: 3.167
Authors: Sohail Rana; Patricia E Houston; Winfred C Wang; Rathi V Iyer; Jonathan Goldsmith; James F Casella; Caroline K Reed; Zora R Rogers; Myron A Waclawiw; Bruce Thompson Journal: Pediatrics Date: 2014-09 Impact factor: 7.124
Authors: Aimé Lukusa Kazadi; René Makuala Ngiyulu; Jean Lambert Gini-Ehungu; Jean Marie Mbuyi-Muamba; Michel Ntetani Aloni Journal: Anemia Date: 2017-01-30
Authors: George O Adjei; Seth K Amponsah; Bamenla Q Goka; Christabel Enweronu-Laryea; Lorna Renner; Abdul Malik Sulley; Michael Alifrangis; Jorgen A L Kurtzhals Journal: Curr Ther Res Clin Exp Date: 2019-01-12