Literature DB >> 22669528

Ocular and orbital metastases presenting as a first sign of gastric adenocarcinoma.

Ranju Sitaula1, Gulshan Bahadur Shrestha, Nabin Paudel, Jeevan Kumar Shrestha.   

Abstract

The authors report a case of simultaneous choroidal and orbital metastases with optic nerve involvement presenting as an initial manifestation of gastric adenocarcinoma. To our knowledge, this is the first case of its kind reported in the literature where a 60 years male presented with 6 months history of progressive painful diminution of vision in his left eye associated with inward and upward rotation of the same globe. Examination of left eye revealed displacement of the globe superomedially by an inferolateral mass with restriction of ocular motility in levoversion. Fundus examination showed exudative retinal detachment with a subretinal mass which was supported by the ocular ultrasonography. Intraocular and orbital tumour was demonstrated by CT. Endoscopic biopsy revealed adenocarcinoma of the stomach. The left orbit was exenterated and specimen was sent for histopathological examination which confirmed the presence of same metastatic tumour cells in the eye and orbit. The patient underwent chemotherapy and radiotherapy for gastric carcinoma but the patient died after 6 months.

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Year:  2011        PMID: 22669528      PMCID: PMC3233916          DOI: 10.1136/bcr.10.2011.4927

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases.

Authors:  A P Ferry; R L Font
Journal:  Arch Ophthalmol       Date:  1974-10

2.  Survey of 520 eyes with uveal metastases.

Authors:  C L Shields; J A Shields; N E Gross; G P Schwartz; S E Lally
Journal:  Ophthalmology       Date:  1997-08       Impact factor: 12.079

3.  Tumors metastatic to the orbit.

Authors:  C L Shields; J A Shields; M Peggs
Journal:  Ophthalmic Plast Reconstr Surg       Date:  1988       Impact factor: 1.746

  3 in total
  1 in total

1.  Sclerosing Signet Ring Cell Carcinoma of the Lacrimal Gland: A Potentially New Primary Entity.

Authors:  Frederick A Jakobiec; Edith R Reshef; Lina Ma; Martin K Selig; Daniel R Lefebvre; Anna M Stagner
Journal:  Ocul Oncol Pathol       Date:  2020-02-07
  1 in total

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