Literature DB >> 2266741

Detailed visualization of pulsatile flow fields produced by modelled arterial stenoses.

M Ojha1, R S Cobbold, K W Johnston, R L Hummel.   

Abstract

A multiple trace photochromic method was used to visualize the pulsatile flow field created by modelled arterial stenoses of 38% and 65% area reductions. Using flow parameters similar to those of a medium sized artery in man, the flow patterns at seven axial locations in relation to the stenosis were simultaneously photographed at various times throughout the flow cycle. With the 65% stenosis, the wall shear stress in the vicinity of the reattachment point was found to fluctuate quite strongly during the turbulent phase of the flow cycle, giving rise to instantaneous shear stresses that were at least eight times larger than those measured upstream. For the 38% stenosis, much smaller shear stresses were observed. These and other results are described in detail.

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Year:  1990        PMID: 2266741     DOI: 10.1016/0141-5425(90)90055-r

Source DB:  PubMed          Journal:  J Biomed Eng        ISSN: 0141-5425


  5 in total

1.  Neutrophil adhesion on endothelial cells in a novel asymmetric stenosis model: effect of wall shear stress gradients.

Authors:  Leonie Rouleau; Ian B Copland; Jean-Claude Tardif; Rosaire Mongrain; Richard L Leask
Journal:  Ann Biomed Eng       Date:  2010-04-13       Impact factor: 3.934

2.  Detection of early atherosclerosis by analysis of ultrasonic Doppler signals produced by mural flow disturbances.

Authors:  T M Robinson; J W Lee; V C Roberts
Journal:  Med Biol Eng Comput       Date:  1994-11       Impact factor: 2.602

3.  Simulation of three-dimensional pulsatile flow through an asymmetric stenosis.

Authors:  A S Dvinsky; M Ojha
Journal:  Med Biol Eng Comput       Date:  1994-03       Impact factor: 2.602

4.  Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow.

Authors:  Thomas V Colace; Scott L Diamond
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-10-25       Impact factor: 8.311

Review 5.  Transport physics and biorheology in the setting of hemostasis and thrombosis.

Authors:  L F Brass; S L Diamond
Journal:  J Thromb Haemost       Date:  2016-03-30       Impact factor: 5.824

  5 in total

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