OBJECTIVES: To determine relationship of body mass index (BMI) with multiple cardiovascular risk factors. METHODS: Population-based surveys were performed and 1893 subjects aged 20-59 years evaluated. Data were collected using anthropometry and fasting glucose and lipid estimation. Statistical analyses were performed using curve fit and logistic regression. RESULTS: Body mass index was correlated significantly (Rho, R(2)) with weight (0.80, 0.64), waist (0.74, 0.55) and waist hip ratio (0.24, 0.06) (P < 0.05). Linear relationship was observed with systolic blood pressure (SBP) (0.39, 0.15), diastolic blood pressure (DBP) (0.29, 0.08), fasting glucose (0.13, 0.02), cholesterol (0.10, 0.01), high-density lipoprotein cholesterol (HDL-c) (-0.16, 0.03), and triglycerides (0.12, 0.01). Significant trends of risk factors with each increasing BMI unit (χ(2) test, P < 0.001) were observed for hypertension (HTN) (214.4), diabetes (29.5), metabolic syndrome (108.9), and low HDL-c (40.5), and weaker trends with hypercholesterolemia (20.6), and hypertriglyceridemia (9.6). There was exponential relationship of BMI with age- and sex-adjusted odds ratios for HTN, diabetes, and metabolic syndrome. CONCLUSION: Metabolic cardiovascular risk factors continuously worsen with increasing BMI.
OBJECTIVES: To determine relationship of body mass index (BMI) with multiple cardiovascular risk factors. METHODS: Population-based surveys were performed and 1893 subjects aged 20-59 years evaluated. Data were collected using anthropometry and fasting glucose and lipid estimation. Statistical analyses were performed using curve fit and logistic regression. RESULTS: Body mass index was correlated significantly (Rho, R(2)) with weight (0.80, 0.64), waist (0.74, 0.55) and waist hip ratio (0.24, 0.06) (P < 0.05). Linear relationship was observed with systolic blood pressure (SBP) (0.39, 0.15), diastolic blood pressure (DBP) (0.29, 0.08), fasting glucose (0.13, 0.02), cholesterol (0.10, 0.01), high-density lipoprotein cholesterol (HDL-c) (-0.16, 0.03), and triglycerides (0.12, 0.01). Significant trends of risk factors with each increasing BMI unit (χ(2) test, P < 0.001) were observed for hypertension (HTN) (214.4), diabetes (29.5), metabolic syndrome (108.9), and low HDL-c (40.5), and weaker trends with hypercholesterolemia (20.6), and hypertriglyceridemia (9.6). There was exponential relationship of BMI with age- and sex-adjusted odds ratios for HTN, diabetes, and metabolic syndrome. CONCLUSION: Metabolic cardiovascular risk factors continuously worsen with increasing BMI.
Authors: Abel Romero-Corral; Victor M Montori; Virend K Somers; Josef Korinek; Randal J Thomas; Thomas G Allison; Farouk Mookadam; Francisco Lopez-Jimenez Journal: Lancet Date: 2006-08-19 Impact factor: 79.321
Authors: Sun Ha Jee; Jae Woong Sull; Jungyong Park; Sang-Yi Lee; Heechoul Ohrr; Eliseo Guallar; Jonathan M Samet Journal: N Engl J Med Date: 2006-08-22 Impact factor: 91.245
Authors: Kenneth F Adams; Arthur Schatzkin; Tamara B Harris; Victor Kipnis; Traci Mouw; Rachel Ballard-Barbash; Albert Hollenbeck; Michael F Leitzmann Journal: N Engl J Med Date: 2006-08-22 Impact factor: 91.245
Authors: Vellani Haridasan; K F Rajesh; C G Sajeev; G Rajesh; Cicy Bastion; D Vinayakumar; P Kadermuneer; Dolly Mathew; Biju George; M N Krishnan Journal: Indian Heart J Date: 2016-03-02