Literature DB >> 2266425

Lowering the cost of lowering the cholesterol: a formulary policy for lovastatin.

F A Lederle1, E M Rogers.   

Abstract

OBJECTIVES: To describe a medical center policy designed to contain the cost of using the lipid-lowering drug lovastatin in a primary care setting, to examine the effect of the policy on cost containment, and to examine physician acceptance of the policy.
SETTING: A Veterans Affairs medical center.
INTERVENTIONS: The policy made lovastatin available to physicians when failure of therapy with diet and two first-line drugs was documented on an order form. The form also contained educational information including prices and recommended niacin as the drug treatment of first choice for most patients.
DESIGN: To evaluate the effect of the policy, lipid-lowering drug use at the medical center was compared with that at a similar center that did not restrict lovastatin use, and with lipid-lowering drug use in the United States as a whole. A written questionnaire was used to survey physician reaction to the policy.
RESULTS: The use of lovastatin as a percentage of total lipid-lowering drug use at the center with the lovastatin policy was one-fourth that at the other center or nationwide, and the use of niacin was four times greater (p less than 0.0001). The estimated savings in drug costs to the center with the lovastatin policy due to these differences was more than $30,000 per year. In the survey of physicians affected by the policy (n = 78, response rate = 100%), less than one-fourth viewed it unfavorably, and 90% favored this policy over restricting the drug to a subspecialty clinic.
CONCLUSION: The authors' experience indicates that a formulary policy that permits limited use of an expensive drug in a primary care setting can contain costs in a way that is acceptable to physicians. A policy of this type could be useful to the increasing number of health care provider organizations that cover the cost of outpatient medications.

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Year:  1990        PMID: 2266425     DOI: 10.1007/bf02600868

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  15 in total

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Review 2.  Choice of cholesterol-lowering drugs.

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Review 3.  Use of antimicrobial agents in a university teaching hospital. Evolution of a comprehensive control program.

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5.  Preferences and practices of Americans and their physicians in antihypertensive therapy.

Authors:  G Gallup; H E Cotugno
Journal:  Am J Med       Date:  1986-12-31       Impact factor: 4.965

6.  Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based "detailing".

Authors:  J Avorn; S B Soumerai
Journal:  N Engl J Med       Date:  1983-06-16       Impact factor: 91.245

7.  The failure of physician education as a cost containment strategy. Report of a prospective controlled trial at a university hospital.

Authors:  S A Schroeder; L P Myers; S J McPhee; J A Showstack; D W Simborg; S A Chapman; J K Leong
Journal:  JAMA       Date:  1984-07-13       Impact factor: 56.272

8.  Therapeutic use of albumin: 2.

Authors:  M R Alexander; B Alexander; A L Mustion; R Spector; C B Wright
Journal:  JAMA       Date:  1982-02-12       Impact factor: 56.272

9.  Therapeutic response to lovastatin (mevinolin) in nonfamilial hypercholesterolemia. A multicenter study. The Lovastatin Study Group II.

Authors: 
Journal:  JAMA       Date:  1986-11-28       Impact factor: 56.272

10.  Cholesterol-lowering effects of psyllium hydrophilic mucilloid for hypercholesterolemic men.

Authors:  J W Anderson; N Zettwoch; T Feldman; J Tietyen-Clark; P Oeltgen; C W Bishop
Journal:  Arch Intern Med       Date:  1988-02
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  2 in total

1.  Formulary policy for cholesterol reduction.

Authors: 
Journal:  J Gen Intern Med       Date:  1991 May-Jun       Impact factor: 5.128

2.  Variation in Formulary Management Practices Within the Department of Veterans Affairs Health Care System.

Authors:  Thomas R Radomski; Chester B Good; Carolyn T Thorpe; Xinhua Zhao; Zachary A Marcum; Peter A Glassman; John Lowe; Maria K Mor; Michael J Fine; Walid F Gellad
Journal:  J Manag Care Spec Pharm       Date:  2015-12-14
  2 in total

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