Literature DB >> 22663190

Polyhydroxylated steroidal glycosides from Paris polyphylla.

Li-Ping Kang1, Yi-Xun Liu, Tolga Eichhorn, Else Dapat, He-shui Yu, Yang Zhao, Cheng-Qi Xiong, Chao Liu, Thomas Efferth, Bai-Ping Ma.   

Abstract

Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C(21) steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 β-d-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells.

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Year:  2012        PMID: 22663190     DOI: 10.1021/np300045g

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.

Authors:  Chao Zhang; Qingrui Li; Guozheng Qin; Yi Zhang; Chaoying Li; Liwen Han; Rongchun Wang; Shudan Wang; Haixia Chen; Kechun Liu; Chengwei He
Journal:  Chin Med       Date:  2021-05-31       Impact factor: 5.455

Review 2.  Untiring Researches for Alternative Resources of Rhizoma Paridis.

Authors:  Xu-Jie Qin; Wei Ni; Chang-Xiang Chen; Hai-Yang Liu
Journal:  Nat Prod Bioprospect       Date:  2018-07-04

Review 3.  Bioactive secondary metabolites in Paris polyphylla Sm. and their biological activities: A review.

Authors:  Chandra Bahadur Thapa; Mukti Ram Paudel; Hari Data Bhattarai; Krishna Kumar Pant; Hari Prasad Devkota; Yagya Prasad Adhikari; Bijaya Pant
Journal:  Heliyon       Date:  2022-02-17

Review 4.  Recent advances in steroidal saponins biosynthesis and in vitro production.

Authors:  Swati Upadhyay; Gajendra Singh Jeena; Rakesh Kumar Shukla
Journal:  Planta       Date:  2018-05-10       Impact factor: 4.116

5.  Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla.

Authors:  Ling-Yu Jin; Ting-Xiang Lu; Xu-Jie Qin; Wei Ni; Huan Yan; Yu Chen; Hui Liu; Hong-Ping He; Hai-Yang Liu
Journal:  Nat Prod Bioprospect       Date:  2016-06-02

6.  Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research.

Authors:  Chen Zhang; Yerlan Idelbayev; Nicholas Roberts; Yiwen Tao; Yashwanth Nannapaneni; Brendan M Duggan; Jie Min; Eugene C Lin; Erik C Gerwick; Garrison W Cottrell; William H Gerwick
Journal:  Sci Rep       Date:  2017-10-27       Impact factor: 4.379

  6 in total

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