Literature DB >> 22663012

Promises from trametinib in RAF active tumors.

Edward A Sausville.   

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Year:  2012        PMID: 22663012     DOI: 10.1056/NEJMe1205654

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  3 in total

1.  Therapeutic effects of targeting RAS-ERK signaling in giant congenital melanocytic nevi.

Authors:  Qingxiong Yu; Min Wu; Lingling Sheng; Qingfeng Li; Feng Xie
Journal:  Am J Transl Res       Date:  2018-04-15       Impact factor: 4.060

2.  Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.

Authors:  Pei Jye Voon; Eric X Chen; Helen X Chen; Albert C Lockhart; Solmaz Sahebjam; Karen Kelly; Ulka N Vaishampayan; Vivek Subbiah; Albiruni R Razak; Daniel J Renouf; Sebastien J Hotte; Arti Singh; Philippe L Bedard; Aaron R Hansen; S Percy Ivy; Lisa Wang; Lee-Anne Stayner; Lillian L Siu; Anna Spreafico
Journal:  J Exp Clin Cancer Res       Date:  2022-02-07

3.  A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway: TRAM-01.

Authors:  Sébastien Perreault; Valérie Larouche; Uri Tabori; Cynthia Hawkin; Sarah Lippé; Benjamin Ellezam; Jean-Claude Décarie; Yves Théoret; Marie-Élaine Métras; Serge Sultan; Édith Cantin; Marie-Ève Routhier; Maxime Caru; Geneviève Legault; Éric Bouffet; Lucie Lafay-Cousin; Juliette Hukin; Craig Erker; Nada Jabado
Journal:  BMC Cancer       Date:  2019-12-27       Impact factor: 4.430

  3 in total

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