| Literature DB >> 22662095 |
Melinda G Simon1, Robert Lin, Jeffrey S Fisher, Abraham P Lee.
Abstract
Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion.Year: 2012 PMID: 22662095 PMCID: PMC3365347 DOI: 10.1063/1.3687400
Source DB: PubMed Journal: Biomicrofluidics ISSN: 1932-1058 Impact factor: 2.800