Literature DB >> 22658934

Dietary factors and risk of kidney stone: a case-control study in southern China.

Meng Dai1, Ai Zhao, Aiping Liu, Lili You, Peiyu Wang.   

Abstract

OBJECTIVE: Formation of kidney stones is a multifactorial disease, and diet and lifestyle are suggested to contribute remarkably to increased prevalence. The population of Guangzhou, China has a high prevalence rate of kidney stones; however, its risk factors are still unknown. The aim of this study was to investigate the dietary risk factors for kidney stones in southern China.
DESIGN: A case-control study was carried out.
SETTING: This study was carried out at the Department of Health Management Center, Guangzhou Nanfang Hospital, China.
SUBJECTS: This study involved 1,019 newly diagnosed kidney stone patients and 987 healthy control subjects. INTERVENTION: A questionnaire regarding dietary patterns and supplements was used to investigate the risk factors for kidney stone formation. MAIN OUTCOME MEASURE: Food intake frequency, beverage and alcohol consumption, food supplements, and anthropometry were assessed.
RESULTS: In the analysis, we found positive associations of kidney stones with consumption of grains (odds ratio [OR] = 2.08; 95% confidence interval [CI] = 1.08, 4.02) and bean products (OR = 3.50; 95% CI = 1.61, 7.59) in women. The variable "fluid drinking" showed a significant protective effect against kidney stones in men (OR = 0.57; 95% CI = 0.36, 0.88). Consuming leafy vegetables more than 3 times per day was positively associated with stones in both men and women (OR = 2.02; 95% CI = 1.04, 3.91 and OR = 3.86; 95% CI = 1.48, 10.04, respectively). Other dietary factors, dietary supplements, and specific food were not related to kidney stone formation in Guangzhou, China.
CONCLUSION: The results confirmed that specific diet can affect stone formation in the Chinese population, and varied risk factors were found for different genders.
Copyright © 2013 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2012        PMID: 22658934     DOI: 10.1053/j.jrn.2012.04.003

Source DB:  PubMed          Journal:  J Ren Nutr        ISSN: 1051-2276            Impact factor:   3.655


  12 in total

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