Literature DB >> 2265772

Experimental study on the fractionation schedule for proton irradiation of uveal melanoma.

G Wollensak1, L Zografos, C Perret, E Egger, H Fritz-Niggli.   

Abstract

Greene melanoma in the anterior chamber of rabbits was irradiated by protons to find the isoeffect curve for proton irradiation fractionated into one, two, three or four doses. The isoeffect curve for tumor tissue remained constant between one- and three-dose fractionations and rose with four-dose fractionation. The isoeffect curve for normal tissue approximately followed the Ellis equation. Therefore, the optimal irradiation schedule should be in the range of three fractions because this best spares normal tissue while delivering a tumoricidal dose to the lesion. The relative reduction of the total dose from four- to one-dose fractions of intraoperative irradiation should be 20%.

Entities:  

Mesh：

Year:  1990        PMID： 2265772     DOI： 10.1007/bf00918491

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN： 0721-832X            Impact factor:   3.117


  41 in total

1.  The risk of enucleation after proton beam irradiation of uveal melanoma.

Authors:  K M Egan; E S Gragoudas; J M Seddon; R J Glynn; J E Munzenreider; M Goitein; L Verhey; M Urie; A Koehler
Journal:  Ophthalmology       Date:  1989-09       Impact factor: 12.079

2.  Comparison of survival rates for patients with uveal melanoma after treatment with proton beam irradiation or enucleation.

Authors:  J M Seddon; E S Gragoudas; D M Albert; C C Hsieh; L Polivogianis; G R Friedenberg
Journal:  Am J Ophthalmol       Date:  1985-03-15       Impact factor: 5.258

3.  The phenomenon of reoxygenation and its implications for fractionated radiotherapy.

Authors:  R F Kallman
Journal:  Radiology       Date:  1972-10       Impact factor: 11.105

4.  A simplification in the use of the NSD concept in practical radiotherapy.

Authors:  C G Orton; F Ellis
Journal:  Br J Radiol       Date:  1973-07       Impact factor: 3.039

5.  Proton-beam irradiated epithelioid cell melanoma of the ciliary body.

Authors:  K M Zinn; K Stein/Pokorny; F A Jakobiec; A H Friedman; E S Gragoudas; R Ritch
Journal:  Ophthalmology       Date:  1981-12       Impact factor: 12.079

6.  Progress in low-LET heavy particle therapy: intracranial and paracranial tumors and uveal melanomas.

Authors:  M Austin-Seymour; J E Munzenrider; M Goitein; R Gentry; E Gragoudas; A M Koehler; P McNulty; E Osborne; D K Ryugo; J Seddon
Journal:  Radiat Res Suppl       Date:  1985

7.  Comparison of uveal melanoma growth rates with mitotic index and mortality.

Authors:  J D Gass
Journal:  Arch Ophthalmol       Date:  1985-07

8.  Neovascular glaucoma after helium ion irradiation for uveal melanoma.

Authors:  M K Kim; D H Char; J L Castro; W M Saunders; G T Chen; R D Stone
Journal:  Ophthalmology       Date:  1986-02       Impact factor: 12.079

9.  [Report on the conservative treatment of melanoma of the uvea at the Lausanne University Ophthalmologic Clinic].

Authors:  L Zografos; C Gailloud; C Perret; S Uffer; S Raimondi; L Chamot; S Carrel; R Greiner
Journal:  Klin Monbl Augenheilkd       Date:  1988-05       Impact factor: 0.700

10.  Regression of posterior uveal malignant melanomas after cobalt plaque radiotherapy.

Authors:  J J Augsburger; B T McNeary; H von Below; J W Gamel; J A Shields; L W Brady; A M Markoe; J L Day
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1986       Impact factor: 3.117
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.