Literature DB >> 22657532

Western blot analysis as an aid for the diagnosis of cutaneous leishmaniasis due to Leishmania major.

Christelle Pomares1, Laura Despierres, Pascal del Giudice, Pascal Delaunay, Grégory Michel, Bernard Ferrua, Pierre Marty.   

Abstract

Cutaneous leishmaniasis (CL) due to Leishmania major is endemic in the Old World. To evaluate the diagnostic value of Western blot (WB) compared with IFAT, we tested serum samples from 45 patients with proven CL. Twenty-one (47%) patients were positive by IFAT and all patients were positive by WB with specific bands against 14kDa and/or 18kDa Leishmania antigens. Our results suggest that WB could be a useful non-invasive tool for the diagnosis of CL caused by L. major.
Copyright © 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22657532     DOI： 10.1016/j.trstmh.2012.03.001

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN： 0035-9203            Impact factor:   2.184


  7 in total

1.  Diagnosing Cutaneous leishmaniasis using Fluorescence in Situ Hybridization: the Sri Lankan Perspective.

Authors:  Thilini Dilhara Jayasena Kaluarachchi; Manjula Manoji Weerasekera; Andrew J McBain; Shalindra Ranasinghe; Renu Wickremasinghe; Surangi Yasawardene; Nisal Jayanetti; Rajitha Wickremasinghe
Journal:  Pathog Glob Health       Date:  2019-08-20       Impact factor: 2.894

Review 2.  Complementary exams in the diagnosis of American tegumentary leishmaniasis.

Authors:  Ciro Martins Gomes; Natália Aparecida de Paula; Orlando Oliveira de Morais; Killarney Ataíde Soares; Ana Maria Roselino; Raimunda Nonata Ribeiro Sampaio
Journal:  An Bras Dermatol       Date:  2014 Sep-Oct       Impact factor: 1.896

3.  Diagnostic performance of ELISA, IFAT and Western blot for the detection of anti-Leishmania infantum antibodies in cats using a Bayesian analysis without a gold standard.

Authors:  Maria Flaminia Persichetti; Laia Solano-Gallego; Angela Vullo; Marisa Masucci; Pierre Marty; Pascal Delaunay; Fabrizio Vitale; Maria Grazia Pennisi
Journal:  Parasit Vectors       Date:  2017-03-13       Impact factor: 3.876

4.  Utility of Western Blot Analysis for the Diagnosis of Cutaneous Leishmaniasis.

Authors:  Marzieh Ashrafmansouri; Bahador Sarkari; Gholamreza Hatam; Parvaneh Habibi; Samaneh Abdolahi Khabisi
Journal:  Iran J Parasitol       Date:  2015 Oct-Dec       Impact factor: 1.012

5.  Detection of Potentially Diagnostic Leishmania Antigens with Western Blot Analysis of Sera from Patients with Cutaneous and Visceral Leishmaniases.

Authors:  Seyyed Javad Seyyedtabaei; Ali Rostami; Ali Haghighi; Mehdi Mohebali; Bahram Kazemi; Shirzad Fallahi; Adel Spotin
Journal:  Iran J Parasitol       Date:  2017 Apr-Jun       Impact factor: 1.012

Review 6.  Place of Serology in the Diagnosis of Zoonotic Leishmaniases With a Focus on Visceral Leishmaniasis Due to Leishmania infantum.

Authors:  Maude F Lévêque; Laurence Lachaud; Loïc Simon; Emilie Battery; Pierre Marty; Christelle Pomares
Journal:  Front Cell Infect Microbiol       Date:  2020-02-25       Impact factor: 5.293

7.  First Serological Study Revealing High Humoral Response and Evidence for Antigenic Heterogeneity in Leishmania donovani Induced CL in Sri Lanka.

Authors:  Bhagya Deepachandi; Sudath Weerasinghe; Samantha Ranasinghe; Thisira P Andrahennadi; Mahendra N Wickramanayake; Shantha Siri; Nadira Karunaweera; Vishvanath Chandrasekharan; Mitali Chatterjee; Preethi Soysa; Yamuna Siriwardana
Journal:  Biomed Res Int       Date:  2020-09-29       Impact factor: 3.411
  7 in total

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