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Literature DB >> 22653208

Outlook for the next 5 years in drug innovation.

Roy Berggren, Martin Møller, Rachel Moss, Pawel Poda, Katarzyna Smietana.

Abstract

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Year: 2012 PMID： 22653208 DOI： 10.1038/nrd3744

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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2 in total

Review 1. How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors: Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal: Nat Rev Drug Discov Date: 2010-02-19 Impact factor: 84.694

2. Pharmaceutical R&D: the road to positive returns.

Authors: Eric David; Tony Tramontin; Rodney Zemmel
Journal: Nat Rev Drug Discov Date: 2009-08 Impact factor: 84.694

2 in total

17 in total

1. Towards drug repositioning: a unified computational framework for integrating multiple aspects of drug similarity and disease similarity.

Authors: Ping Zhang; Fei Wang; Jianying Hu
Journal: AMIA Annu Symp Proc Date: 2014-11-14

Review 2. Market access of cancer drugs in European countries: improving resource allocation.

Authors: Kim Pauwels; Isabelle Huys; Minne Casteels; Katelijne De Nys; Steven Simoens
Journal: Target Oncol Date: 2013-11-19 Impact factor: 4.493

3. Emphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.

Authors: Jan-Willem van de Loo; Dominika Trzaska; Karim Berkouk; Maria Vidal; Ruxandra Draghia-Akli
Journal: Oncologist Date: 2012

4. Frontier of therapeutic antibody discovery: The challenges and how to face them.

Authors: Zhi-Jian Lu; Su-Jun Deng; Da-Gang Huang; Yun He; Ming Lei; Li Zhou; Pei Jin
Journal: World J Biol Chem Date: 2012-12-26

Review 5. "Digital biomarkers" in preclinical heart failure models - a further step towards improved translational research.

Authors: Alexander Schmidt; Jakob Balitzki; Ljubica Grmaca; Julia Vogel; Philip Boehme; Katharina Boden; Jörg Hüser; Hubert Truebel; Thomas Mondritzki
Journal: Heart Fail Rev Date: 2022-08-24 Impact factor: 4.654

Outlook for the next 5 years in drug innovation.

Review 1. How to improve R&D productivity: the pharmaceutical industry's grand challenge.

2. Pharmaceutical R&D: the road to positive returns.

1. Towards drug repositioning: a unified computational framework for integrating multiple aspects of drug similarity and disease similarity.

Review 2. Market access of cancer drugs in European countries: improving resource allocation.

3. Emphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.

4. Frontier of therapeutic antibody discovery: The challenges and how to face them.

Review 5. "Digital biomarkers" in preclinical heart failure models - a further step towards improved translational research.

Review 6. Drug Development for Hypertension: Do We Need Another Antihypertensive Agent for Resistant Hypertension?

7. Decline in new drug launches: myth or reality? Retrospective observational study using 30 years of data from the UK.

Review 8. Repurposing existing therapeutics, its importance in oncology drug development: Kinases as a potential target.

9. Construction of drug network based on side effects and its application for drug repositioning.

10. Target mRNA inhibition by oligonucleotide drugs in man.