Literature DB >> 22653200

Revitalizing psychiatric drug discovery.

Martin Sarter1, Mark Tricklebank.   

Abstract

Psychiatric drug discovery needs to close the systems neuroscience gap to improve the clinical success rates of candidate drugs with novel mechanisms of action.

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Year:  2012        PMID： 22653200     DOI： 10.1038/nrd3755

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  5 in total

1.  Toward new approaches to psychotic disorders: the NIMH Research Domain Criteria project.

Authors:  Bruce N Cuthbert; Thomas R Insel
Journal:  Schizophr Bull       Date:  2010-10-07       Impact factor: 9.306

2.  Medicine. The future of psychiatric research: genomes and neural circuits.

Authors:  Huda Akil; Sydney Brenner; Eric Kandel; Kenneth S Kendler; Mary-Claire King; Edward Scolnick; James D Watson; Huda Y Zoghbi
Journal:  Science       Date:  2010-03-26       Impact factor: 47.728

Review 3.  Review of clinical correlates of P50 sensory gating abnormalities in patients with schizophrenia.

Authors:  David Potter; Ann Summerfelt; James Gold; Robert W Buchanan
Journal:  Schizophr Bull       Date:  2006-02-09       Impact factor: 9.306

Review 4.  Optogenetic investigation of neural circuits underlying brain disease in animal models.

Authors:  Kay M Tye; Karl Deisseroth
Journal:  Nat Rev Neurosci       Date:  2012-03-20       Impact factor: 34.870

Review 5.  A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits.

Authors:  Steven C Leiser; Mark R Bowlby; Thomas A Comery; John Dunlop
Journal:  Pharmacol Ther       Date:  2009-04-05       Impact factor: 12.310
  5 in total
  4 in total

1.  Opportunities and challenges in modeling human brain disorders in transgenic primates.

Authors:  Charles G Jennings; Rogier Landman; Yang Zhou; Jitendra Sharma; Julia Hyman; J Anthony Movshon; Zilong Qiu; Angela C Roberts; Anna Wang Roe; Xiaoqin Wang; Huihui Zhou; Liping Wang; Feng Zhang; Robert Desimone; Guoping Feng
Journal:  Nat Neurosci       Date:  2016-08-26       Impact factor: 24.884

2.  Editorial (Thematic Selection: Inflammatory and Immune Responses in Depression).

Authors:  Abhay Sharma
Journal:  Curr Neuropharmacol       Date:  2016       Impact factor: 7.363

3.  Behavioral-Cognitive Targets for Cholinergic Enhancement.

Authors:  Martin Sarter
Journal:  Curr Opin Behav Sci       Date:  2015-01-15

4.  Rescuing the attentional performance of rats with cholinergic losses by the M1 positive allosteric modulator TAK-071.

Authors:  Aaron Kucinski; Kyra B Phillips; Ajeesh Koshy Cherian; Martin Sarter
Journal:  Psychopharmacology (Berl)       Date:  2019-10-16       Impact factor: 4.530
  4 in total

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