Literature DB >> 22652997

Novel therapies, high-risk pediatric research, and the prospect of benefit: learning from the ethical disagreements.

Inmaculada de Melo-Martín1, Dolan Sondhi, Ronald G Crystal.   

Abstract

Mesh:

Year:  2012        PMID: 22652997      PMCID: PMC3369294          DOI: 10.1038/mt.2012.90

Source DB:  PubMed          Journal:  Mol Ther        ISSN: 1525-0016            Impact factor:   11.454


× No keyword cloud information.
  56 in total

1.  Clinical research. Gene therapists celebrate a decade of progress.

Authors:  Jocelyn Kaiser
Journal:  Science       Date:  2011-10-07       Impact factor: 47.728

2.  Preclinical studies of human disease: time to take methodological quality seriously.

Authors:  H Bart van der Worp; Malcolm R Macleod
Journal:  J Mol Cell Cardiol       Date:  2011-04-29       Impact factor: 5.000

3.  Does it matter whether investigators intend to benefit research subjects?

Authors:  David Wendler; Emily Abdoler
Journal:  Kennedy Inst Ethics J       Date:  2010-12

4.  Harmonization of ethics policies in pediatric research.

Authors:  Valarie Blake; Steve Joffe; Eric Kodish
Journal:  J Law Med Ethics       Date:  2011       Impact factor: 1.718

5.  Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.

Authors:  Samuel G Jacobson; Artur V Cideciyan; Ramakrishna Ratnakaram; Elise Heon; Sharon B Schwartz; Alejandro J Roman; Marc C Peden; Tomas S Aleman; Sanford L Boye; Alexander Sumaroka; Thomas J Conlon; Roberto Calcedo; Ji-Jing Pang; Kirsten E Erger; Melani B Olivares; Cristina L Mullins; Malgorzata Swider; Shalesh Kaushal; William J Feuer; Alessandro Iannaccone; Gerald A Fishman; Edwin M Stone; Barry J Byrne; William W Hauswirth
Journal:  Arch Ophthalmol       Date:  2011-09-12

6.  Eschewing definitions of the therapeutic misconception: a family resemblance analysis.

Authors:  Daniel S Goldberg
Journal:  J Med Philos       Date:  2011-05-23

7.  Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.

Authors:  Marina Cavazzana-Calvo; Emmanuel Payen; Olivier Negre; Gary Wang; Kathleen Hehir; Floriane Fusil; Julian Down; Maria Denaro; Troy Brady; Karen Westerman; Resy Cavallesco; Beatrix Gillet-Legrand; Laure Caccavelli; Riccardo Sgarra; Leila Maouche-Chrétien; Françoise Bernaudin; Robert Girot; Ronald Dorazio; Geert-Jan Mulder; Axel Polack; Arthur Bank; Jean Soulier; Jérôme Larghero; Nabil Kabbara; Bruno Dalle; Bernard Gourmel; Gérard Socie; Stany Chrétien; Nathalie Cartier; Patrick Aubourg; Alain Fischer; Kenneth Cornetta; Frédéric Galacteros; Yves Beuzard; Eliane Gluckman; Frederick Bushman; Salima Hacein-Bey-Abina; Philippe Leboulch
Journal:  Nature       Date:  2010-09-16       Impact factor: 49.962

Review 8.  Adverse drug reactions in newborns, infants and toddlers: pediatric pharmacovigilance between present and future.

Authors:  Valentina Fabiano; Chiara Mameli; Gian Vincenzo Zuccotti
Journal:  Expert Opin Drug Saf       Date:  2011-05-09       Impact factor: 4.250

9.  Stem-cell gene therapy for the Wiskott-Aldrich syndrome.

Authors:  Kaan Boztug; Manfred Schmidt; Adrian Schwarzer; Pinaki P Banerjee; Inés Avedillo Díez; Ricardo A Dewey; Marie Böhm; Ali Nowrouzi; Claudia R Ball; Hanno Glimm; Sonja Naundorf; Klaus Kühlcke; Rainer Blasczyk; Irina Kondratenko; László Maródi; Jordan S Orange; Christof von Kalle; Christoph Klein
Journal:  N Engl J Med       Date:  2010-11-11       Impact factor: 91.245

10.  Efficacy of gene therapy for X-linked severe combined immunodeficiency.

Authors:  Salima Hacein-Bey-Abina; Julia Hauer; Annick Lim; Capucine Picard; Gary P Wang; Charles C Berry; Chantal Martinache; Frédéric Rieux-Laucat; Sylvain Latour; Bernd H Belohradsky; Lily Leiva; Ricardo Sorensen; Marianne Debré; Jean Laurent Casanova; Stephane Blanche; Anne Durandy; Frederic D Bushman; Alain Fischer; Marina Cavazzana-Calvo
Journal:  N Engl J Med       Date:  2010-07-22       Impact factor: 91.245

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.