Literature DB >> 22652158

Botulinum toxin type A in cervical dystonia.

R Marvulli1, G Ianieri, G Megna, G Lancioni, R Saggini, M Ranieri, G Cristella, M Megna.   

Abstract

Cervical dystonia is a syndrome characterized by anomalous postures and unintentional repetitive movements of the head and the neck. Aim of this study is to show the effectiveness of the combined treatment botulinum toxin-FKT through the use of a recent methodic of investigation, myoton, and of the classical clinical evaluations, such as Tsui and VAS scales. 15 patients (9 females, 6 males) have been selected. During the initial visit and in the following controls, performed every month, patients have been submitted to physiatric examination, clinical evaluation of the dystonia through the Tsui scale, clinical evaluation of the pain through the VAS scale, myometric evaluation. We obtained a statistical reduction of muscular tone values in passive elongation (t0=16,34±1,23) until 4 month (t4 =16,11±1,23), when we performed a second infiltration. After 4 months from the second infiltration (t8=15,99±1,11) value did not present more some statistical correlation and was necessary to perform a new infiltration. Values of elasticity, stiffness, Tsui and VAS scale followed the same course of the tone. Our study demonstrates that combined treatment botulinum toxin-FKT is effective. It emerges that if to the treatment with botulinum toxin follows a suitable FKT treatment, the effect of the drug lasts 4 months and not 3 months as described by the literature. Our study has underlined that using myometric measurement we can consider least changes in muscular tone, elasticity and stiffness; we have a broader view of the spastic muscle, and we can better plan appropriate rehabilitative care for each patient.

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Year:  2012        PMID: 22652158     DOI: 10.1177/03946320120250s104

Source DB:  PubMed          Journal:  Int J Immunopathol Pharmacol        ISSN: 0394-6320            Impact factor:   3.219


  2 in total

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Authors:  Ivana Rocha Raslan; Paula Camila Alves de Assis Pereira Matos; Vinícius Boaratti Ciarlariello; Karyme Hussein Daghastanli; Augusto Bragança Reis Rosa; Juliana Harumi Arita; Carolina Sanchez Aranda; Orlando Graziani Povoas Barsottini; José Luiz Pedroso
Journal:  Mov Disord Clin Pract       Date:  2020-11-19

2.  Reduced Neck Muscle Strength and Altered Muscle Mechanical Properties in Cervical Dystonia Following Botulinum Neurotoxin Injections: A Prospective Study.

Authors:  Sirpa Mustalampi; Jari Ylinen; Katariina Korniloff; Adam Weir; Arja Häkkinen
Journal:  J Mov Disord       Date:  2016-01-25
  2 in total

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