Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Bioassays for evaluation of medical products derived from bacterial toxins.

Literature DB >> 22651974

Bioassays for evaluation of medical products derived from bacterial toxins.

Abstract

Bioassays play central role in evaluation of biological products and those derived from bacterial toxins often rely exclusively on in vivo models for assurance of safety and potency. This chapter reviews existing regulatory approved methods designed to provide information on potency and safety of complex biological medicines with an insight into strategies considered for alternative procedures.

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 22651974 DOI： 10.1016/j.mib.2012.05.008

Source DB: PubMed Journal: Curr Opin Microbiol ISSN： 1369-5274 Impact factor: 7.934

Keyword Cloud
Cited

7 in total

Review 1. Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.

Authors: Marco Pirazzini; Ornella Rossetto; Roberto Eleopra; Cesare Montecucco
Journal: Pharmacol Rev Date: 2017-04 Impact factor: 25.468

2. AbobotulinumtoxinA (Dysport^®), OnabotulinumtoxinA (Botox^®), and IncobotulinumtoxinA (Xeomin^®) Neurotoxin Content and Potential Implications for Duration of Response in Patients.

Authors: Malgorzata Field; Andrew Splevins; Philippe Picaut; Marcel van der Schans; Jan Langenberg; Daan Noort; Keith Foster
Journal: Toxins (Basel) Date: 2018-12-13 Impact factor: 4.546

Bioassays for evaluation of medical products derived from bacterial toxins.

Review 1. Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.

2. AbobotulinumtoxinA (Dysport^®), OnabotulinumtoxinA (Botox^®), and IncobotulinumtoxinA (Xeomin^®) Neurotoxin Content and Potential Implications for Duration of Response in Patients.

Review 3. Botulinum Neurotoxin Therapy for Depression: Therapeutic Mechanisms and Future Perspective.

Review 4. Botulinum Toxin: From Poison to Possible Treatment for Spasticity in Spinal Cord Injury.

5. Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples.

6. SiMa Cells for a Serotype Specific and Sensitive Cell-Based Neutralization Test for Botulinum Toxin A and E.

7. Content/Potency Assessment of Botulinum Neurotoxin Type-A by Validated Liquid Chromatography Methods and Bioassays.

Bioassays for evaluation of medical products derived from bacterial toxins.

Review 1. Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.

2. AbobotulinumtoxinA (Dysport®), OnabotulinumtoxinA (Botox®), and IncobotulinumtoxinA (Xeomin®) Neurotoxin Content and Potential Implications for Duration of Response in Patients.

Review 3. Botulinum Neurotoxin Therapy for Depression: Therapeutic Mechanisms and Future Perspective.

Review 4. Botulinum Toxin: From Poison to Possible Treatment for Spasticity in Spinal Cord Injury.

5. Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples.

6. SiMa Cells for a Serotype Specific and Sensitive Cell-Based Neutralization Test for Botulinum Toxin A and E.

7. Content/Potency Assessment of Botulinum Neurotoxin Type-A by Validated Liquid Chromatography Methods and Bioassays.

2. AbobotulinumtoxinA (Dysport^®), OnabotulinumtoxinA (Botox^®), and IncobotulinumtoxinA (Xeomin^®) Neurotoxin Content and Potential Implications for Duration of Response in Patients.