Literature DB >> 22651935

Integration of data systems and technology improves research and collaboration for a superfund research center.

Kevin A Hobbie1, Elena S Peterson, Michael L Barton, Katrina M Waters, Kim A Anderson.   

Abstract

Large collaborative centers are a common model for accomplishing integrated environmental health research. These centers often include various types of scientific domains (e.g., chemistry, biology, bioinformatics) that are integrated to solve some of the nation's key economic or public health concerns. The Superfund Research Center (SRP) at Oregon State University (OSU) is one such center established in 2008 to study the emerging health risks of polycyclic aromatic hydrocarbons while using new technologies both in the field and laboratory. With outside collaboration at remote institutions, success for the center as a whole depends on the ability to effectively integrate data across all research projects and support cores. Therefore, the OSU SRP center developed a system that integrates environmental monitoring data with analytical chemistry data and downstream bioinformatics and statistics to enable complete "source-to-outcome" data modeling and information management. This article describes the development of this integrated information management system that includes commercial software for operational laboratory management and sample management in addition to open-source custom-built software for bioinformatics and experimental data management.

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Year:  2012        PMID: 22651935      PMCID: PMC3460553          DOI: 10.1177/2211068212448428

Source DB:  PubMed          Journal:  J Lab Autom        ISSN: 2211-0682


  5 in total

1.  Applying open-source software to laboratory data management.

Authors:  Glenn A Murray; David P Crocker
Journal:  J Lab Autom       Date:  2010-07-21

2.  A review of electronic laboratory notebooks available in the market today.

Authors:  Michael Rubacha; Anil K Rattan; Stephen C Hosselet
Journal:  J Lab Autom       Date:  2010-03-05

3.  A LEAN approach toward automated analysis and data processing of polymers using proton NMR spectroscopy.

Authors:  Hans de Brouwer; Gerrit Stegeman
Journal:  J Lab Autom       Date:  2010-03-04

4.  LINA: a laboratory inventory system for oligonucleotides, microbial strains, and cell lines.

Authors:  A F Yousef; I M Baggili; G Bartlett; M D Kane; J S Mymryk
Journal:  J Lab Autom       Date:  2010-03-04

5.  Grid-enabled measures: using Science 2.0 to standardize measures and share data.

Authors:  Richard P Moser; Bradford W Hesse; Abdul R Shaikh; Paul Courtney; Glen Morgan; Erik Augustson; Sarah Kobrin; Kerry Y Levin; Cynthia Helba; David Garner; Marsha Dunn; Kisha Coa
Journal:  Am J Prev Med       Date:  2011-05       Impact factor: 5.043

  5 in total
  3 in total

1.  Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry.

Authors:  Erin P Madeen; Ted J Ognibene; Richard A Corley; Tammie J McQuistan; Marilyn C Henderson; William M Baird; Graham Bench; Ken W Turteltaub; David E Williams
Journal:  Chem Res Toxicol       Date:  2016-09-09       Impact factor: 3.739

Review 2.  Data management strategies for multinational large-scale systems biology projects.

Authors:  Wasco Wruck; Martin Peuker; Christian R A Regenbrecht
Journal:  Brief Bioinform       Date:  2012-10-09       Impact factor: 11.622

3.  Raising to the Challenge: Building a Federated Biobank to Accelerate Translational Research-The University Biobank Limburg.

Authors:  Loes Linsen; Kimberly Vanhees; Evi Vanoppen; Kim Ulenaers; Suzanne Driessens; Joris Penders; Veerle Somers; Piet Stinissen; Jean-Luc Rummens
Journal:  Front Med (Lausanne)       Date:  2019-10-22
  3 in total

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