Literature DB >> 2265140

The role of CA 125 in the early diagnosis of progressive disease in ovarian cancer.

M E van der Burg1, F B Lammes, J Verweij.   

Abstract

The role of CA 125 determination in diagnosing progression of ovarian cancer was evaluated in 98 patients of whom forty-nine had progressive disease. An elevated CA 125 level at the time of progression was found in 36 (73%) patients. In 31 (63%) patients CA 125 increase preceded clinical progression for a median time lag of 4.5 months (range 0.5-29.5 months). The combination of serum CA 125, gynecological and general physical examination detected progression in 45 (92%) patients. The additional contribution of second-look surgery, CTscan, chest X-ray and routine laboratory tests was minimal.

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Year:  1990        PMID: 2265140     DOI: 10.1093/oxfordjournals.annonc.a057754

Source DB:  PubMed          Journal:  Ann Oncol        ISSN: 0923-7534            Impact factor:   32.976


  17 in total

1.  The value of abdominal CT scans in decision-making during chemotherapy in ovarian cancer.

Authors:  M A L van Lankveld; P H M Peeters; M A van Eijkeren; V C M Koot; P O Witteveen; W P Th M Mali
Journal:  Med Oncol       Date:  2004       Impact factor: 3.064

2.  Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders.

Authors:  Richard G Moore; Michael Craig Miller; Margaret M Steinhoff; Steven J Skates; Karen H Lu; Geralyn Lambert-Messerlian; Robert C Bast
Journal:  Am J Obstet Gynecol       Date:  2011-12-30       Impact factor: 8.661

3.  Serum HE4 is more suitable as a biomarker than CA125 in Chinese women with benign gynecologic disorders.

Authors:  Yan Zhang; Chunxia Qiao; Lian Li; Xuye Zhao; Yali Li
Journal:  Afr Health Sci       Date:  2014-12       Impact factor: 0.927

4.  Lights and shadows of the tumoral marker CA-125 in ovarian cancer.

Authors:  A Sánchez Muñoz; A González Martín; C Mendiola Fernández
Journal:  Clin Transl Oncol       Date:  2008-08       Impact factor: 3.405

5.  CA 125 and the detection of recurrent ovarian cancer: a reasonably accurate biomarker for a difficult disease.

Authors:  Robert C Bast
Journal:  Cancer       Date:  2010-06-15       Impact factor: 6.860

6.  Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics.

Authors:  Simon D Weaver; Naviya Schuster-Little; Rebecca J Whelan
Journal:  Anal Methods       Date:  2022-03-17       Impact factor: 3.532

7.  Trial of isotretinoin and calcitriol monitored by CA 125 in patients with ovarian cancer.

Authors:  G J Rustin; T G Quinnell; J Johnson; H Clarke; A E Nelstrop; W Bollag
Journal:  Br J Cancer       Date:  1996-11       Impact factor: 7.640

Review 8.  Role of tumour markers in monitoring epithelial ovarian cancer.

Authors:  T Meyer; G J Rustin
Journal:  Br J Cancer       Date:  2000-05       Impact factor: 7.640

9.  Evaluation of CA-125 as an Indicator of Imaging During Follow-up of Carcinoma Ovary: Original Research.

Authors:  Pesona Grace Lucksom; Sonia Mathai; Jaydip Bhaumik; Anik Ghosh
Journal:  J Obstet Gynaecol India       Date:  2020-05-12

10.  CA-125-indicated asymptomatic relapse confers survival benefit to ovarian cancer patients who underwent secondary cytoreduction surgery.

Authors:  Fang Wang; Yanfen Ye; Xia Xu; Xuehui Zhou; Jinhua Wang; Xiaoxiang Chen
Journal:  J Ovarian Res       Date:  2013-02-13       Impact factor: 4.234

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