Literature DB >> 22650003

Small dense LDL: risk factor for coronary artery disease (CAD) and its therapeutic modulation.

Suman B Sharma1, Seema Garg.   

Abstract

Pathogenesis of coronary artery disease (CAD) is multi-factorial and many risk factors are associated with development of CAD. LDL-C has been an important target for therapeutic interventions and has been extensively studied. But, various studies have indicated that estimation of LDL-C is not enough to assess the risk. Moreover, LDL particles vary in their content, density and size which have different physico-chemical properties. In this paper, the role of small dense (sd) LDL in risk assessment for CAD and its response to different therapeutic modalities available have been reviewed.

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Year:  2012        PMID： 22650003

Source DB:  PubMed          Journal:  Indian J Biochem Biophys        ISSN： 0301-1208            Impact factor:   1.918


  7 in total

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Journal:  Diabetes Metab Syndr Obes       Date:  2015-02-04       Impact factor: 3.168

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Journal:  Diabetes Metab Syndr Obes       Date:  2020-12-21       Impact factor: 3.168

7.  RESEARCH (Recognized effect of Statin and ezetimibe therapy for achieving LDL-C Goal), a randomized, doctor-oriented, multicenter trial to compare the effects of higher-dose statin versus ezetimibe-plus-statin on the serum LDL-C concentration of Japanese type-2 diabetes patients design and rationale.

Authors:  Takeshi Inazawa; Kentaro Sakamoto; Takahide Kohro; Raisuke Iijima; Toru Kitazawa; Tsutomu Hirano; Mitsunobu Kawamura; Motoki Tagami; Akira Tanaka; Yasumichi Mori; Tsutomu Yamazaki; Teruo Shiba
Journal:  Lipids Health Dis       Date:  2013-10-05       Impact factor: 3.876
  7 in total

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