Literature DB >> 22648120

Short-term surgical outcomes and operative risks of laparoscopic total gastrectomy (LTG) for gastric carcinoma: experience at a large-volume center.

Oh Jeong1, Seong Yeop Ryu, Xue-Feng Zhao, Mi Ran Jung, Kwang Yong Kim, Young Kyu Park.   

Abstract

BACKGROUND: Despite the popularity of laparoscopic distal gastrectomy (LDG), laparoscopic total gastrectomy (LTG) remains a challenging procedure because of its technical difficulties and possible complications. In this study, the authors evaluated the short-term surgical outcomes and operative risks of LTG.
METHODS: The records of 118 patients who underwent LTG for middle or upper gastric cancer were retrieved from a prospectively constructed database of 1,064 patients who underwent laparoscopic gastrectomy between 2007 and 2011. Surgical outcomes of LTG, such as operative results, postoperative courses, morbidities, and mortality, were investigated and compared with those of LDG patients.
RESULTS: Of the 118 LTG patients, one underwent open conversion and three experienced an intraoperative complication. Mean operating time was 292 ± 88 min, and the mean total number of harvested lymph nodes was 41 ± 16. As compared with the LDG group, the LTG group had a significantly longer operation time (292 vs. 220 min, p < 0.001), and significantly more intraoperative blood loss (256 vs. 191 ml, p = 0.002). The overall morbidity rate after LTG was 22.9%, which was significantly higher than after LDG (12.7%, p = 0.002). There were two postoperative mortalities in the LTG group. The most common complications after LTG were anastomosis leakage (n = 9) and luminal bleeding (n = 9), which were followed by anastomosis stricture (n = 4) and abdominal infection (n = 3). Univariate and multivariate analysis revealed that old age [≥60 years, odds ratio (OR) = 2.55, 95% confidence interval (CI) = 0.95-6.84], intraoperative blood loss >200 ml (OR = 3.33, 95% CI = 1.14-9.70), and D2 lymphadenectomy (OR = 3.87, 95% CI = 1.30-11.55) were independent risk factors for postoperative complications after LTG.
CONCLUSIONS: LTG is a feasible and acceptable procedure for treatment of middle or upper early gastric cancer. Further refinement of anastomosis techniques and considerable experience of laparoscopic gastrectomy are required for proper application of LTG in gastric carcinoma.

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Year:  2012        PMID: 22648120     DOI: 10.1007/s00464-012-2356-7

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  29 in total

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2.  Management and results of proximal anastomotic leaks in a series of 1114 total gastrectomies for gastric carcinoma.

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3.  Laparoscopic gastrectomy with regional lymph node dissection for upper gastric cancer.

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Journal:  Gastric Cancer       Date:  2003       Impact factor: 7.370

4.  Technical feasibility and safety of laparoscopy-assisted total gastrectomy in gastric cancer: a comparative study with laparoscopy-assisted distal gastrectomy.

Authors:  Sang Eok Lee; Keun Won Ryu; Byung Ho Nam; Jun Ho Lee; Young-Woo Kim; Jun Sik Yu; Soo Jeong Cho; Jong Yeul Lee; Chan Gyoo Kim; Il Ju Choi; Myeong Cherl Kook; Sook Ryun Park; Min Ju Kim; Jong Seok Lee
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5.  Laparoscopic pancreas- and spleen-preserving D2 lymph node dissection in advanced (cT2) upper-third gastric cancer.

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6.  Laparoscopically assisted total gastrectomy with lymph node dissection for upper and middle gastric cancer.

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7.  Intracorporeal circular stapling esophagojejunostomy using the transorally inserted anvil (OrVil) after laparoscopic total gastrectomy.

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Review 8.  Current status of laparoscopic gastrectomy for cancer in Japan.

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10.  Clinicopathological features and surgical treatment of gastric cancer in South Korea: the results of 2009 nationwide survey on surgically treated gastric cancer patients.

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Journal:  J Gastric Cancer       Date:  2011-06-30       Impact factor: 3.720

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  31 in total

1.  Present features and future vision of laparoscopy-assisted total gastrectomy (LATG).

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2.  Laparoscopic gastrectomy for gastric cancer in the elderly patients.

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3.  Application of reduced-port laparoscopic total gastrectomy in gastric cancer preserving the pancreas and spleen.

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Journal:  Gastric Cancer       Date:  2014-11-15       Impact factor: 7.370

4.  Role of robot-assisted distal gastrectomy compared to laparoscopy-assisted distal gastrectomy in suprapancreatic nodal dissection for gastric cancer.

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Journal:  Surg Endosc       Date:  2015-07-14       Impact factor: 4.584

5.  Feasibility of laparoscopy-assisted total gastrectomy in patients with clinical stage I gastric cancer.

Authors:  Noriko Wada; Yukinori Kurokawa; Shuji Takiguchi; Tsuyoshi Takahashi; Makoto Yamasaki; Hiroshi Miyata; Kiyokazu Nakajima; Masaki Mori; Yuichiro Doki
Journal:  Gastric Cancer       Date:  2013-02-22       Impact factor: 7.370

6.  Laparoscopic total gastrectomy and gastric cancer genome architecture: lessons, cautions, and promises.

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Journal:  Surg Endosc       Date:  2013-05-10       Impact factor: 4.584

7.  Short-term outcomes of totally laparoscopic total gastrectomy: experience with the first consecutive 112 cases.

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Journal:  World J Surg       Date:  2014-10       Impact factor: 3.352

8.  Reduced anastomotic complications with intracorporeal esophagojejunostomy using endoscopic linear staplers (overlap method) in laparoscopic total gastrectomy for gastric carcinoma.

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9.  Benefits of laparoscopic surgery compared to open standard surgery for gastric carcinoma in elderly patients: propensity score-matching analysis.

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10.  Surgical advantages of reduced-port laparoscopic gastrectomy in gastric cancer.

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Journal:  Surg Endosc       Date:  2016-05-20       Impact factor: 4.584

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