Literature DB >> 22647650

Tumor enucleation for small renal masses.

Nicholas A Laryngakis1, Thomas J Guzzo.   

Abstract

PURPOSE OF REVIEW: The incidence of renal cell carcinoma and the detection of incidental small renal masses are rising. Urologists are faced with difficult management decisions on how to treat patients with small renal masses. Traditionally, the treatment of suspicious renal masses was radical nephrectomy. However, nephron-sparing surgery is the standard of care, when possible, because of the risk of renal insufficiency associated with radical nephrectomy. RECENT
FINDINGS: A large breadth of data have shown that partial nephrectomy has equivalent oncologic outcomes compared to radical nephrectomy. Recently, attempts to further spare renal parenchyma and perform nephron-sparing surgery in anatomically difficult scenarios have led to the development of the enucleation technique. Enucleation is performed by following the natural plane between the peritumor pseudocapsule and the renal parenchyma. This emerging technique was met with skepticism and concern for incomplete tumor removal. However, studies comparing enucleation and partial nephrectomy to date have revealed equivalent oncologic outcomes.
SUMMARY: There has been a greater acceptance of tumor enucleation as a safe alternative for renal masses which are locally confined on preoperative imaging, easily delineated intraoperatively, and do not appear to grossly invade beyond the pseudocapsule.

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Mesh:

Year:  2012        PMID: 22647650     DOI: 10.1097/MOU.0b013e3283551f84

Source DB:  PubMed          Journal:  Curr Opin Urol        ISSN: 0963-0643            Impact factor:   2.309


  5 in total

1.  Laparoscopic radiofrequency ablation-assisted enucleation of Xp11.2 translocation renal cell carcinoma: A case report.

Authors:  Linfeng Xu; Rong Yang; Wei Wang; Yifen Zhang; Weidong Gan
Journal:  Oncol Lett       Date:  2014-06-18       Impact factor: 2.967

Review 2.  Simple Enucleation for Renal Tumors: Indications, Techniques, and Results.

Authors:  Adolfo García García; Tania González León
Journal:  Curr Urol Rep       Date:  2016-01       Impact factor: 3.092

3.  Pseudocapsule of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: a clue for tumor enucleation?

Authors:  Xiangming Cheng; Jian He; Weidong Gan; Xiangshan Fan; Jun Yang; Bin Zhu; Hongqian Guo
Journal:  Int J Clin Exp Pathol       Date:  2015-05-01

Review 4.  A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy.

Authors:  Tobias Klatte; Vincenzo Ficarra; Christian Gratzke; Jihad Kaouk; Alexander Kutikov; Veronica Macchi; Alexandre Mottrie; Francesco Porpiglia; James Porter; Craig G Rogers; Paul Russo; R Houston Thompson; Robert G Uzzo; Christopher G Wood; Inderbir S Gill
Journal:  Eur Urol       Date:  2015-04-22       Impact factor: 20.096

5.  Prevalence and outcomes of peritumor fat involvement following partial nephrectomy for radiologic T1 renal cancer.

Authors:  Mohamed Kamel; Mohamed Elfaramawi; Supria Jadhav; Rodney Davis; Ahmed Saafan; Annashia Sher
Journal:  Urol Ann       Date:  2015 Oct-Dec
  5 in total

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